Impact of a Pre-defined Pacemapping Protocol Use for Ablation of Infrequent Premature Ventricular Complexes: A Prospective, Multicenter Study.
B, Jáuregui ; D, Penela ; J, Fernández-Armenta ; J, Acosta ; C, Terés ; D, Soto-Iglesias ; E, Silva ; A, Ordóñez ; Antonio R, San ; A, Chauca ; JM, Carreño ; C, Scherer ; A, Berruezo
Resumen: Background
Pacemapping (PM) is a useful maneuver for aiding premature ventricular complex (PVC) ablation. Its standalone clinical value is still to be defined.
Objectives
The purpose of this study was to analyze the efficacy of a predefined PM protocol for low-burden PVC ablation, regardless of their site of origin (SOO) and the presence of structural heart disease.
Methods
This was a prospective, nonrandomized, multicenter study. The PM protocol was performed when <1 PVC/min was found. The “target area” was delimited by the 3 best matching points >94% correlation, and 3 radiofreqency (RF) applications were delivered.
Results
Of 185 patients, 105 (57%) underwent activation mapping, 60 (32%) were PM-guided, and 20 (11%) were canceled due to absence of PVCs. Baseline QRS, PVC burden, and outflow tract origin were independent predictors of PM-guided ablation. A higher proportion of right ventricular outflow tract SOO in the PM group (52% vs 40%; P = .03) was observed. Mean target area was 0.6 ± 0.9 cm2. Mean 10-ms isochronal area in local activation time (LAT)-guided procedures was higher (1.7 ± 2.3 cm2; P <.001). Mean number of PM matching points acquired was 39 ± 21 (range 6–98). Mean mapping and RF times were similar in both groups. However, significantly shorter procedural (53 ± 24 vs 61 ± 26 minutes; P = .04) as well as RF times (111 ± 51 vs 149 ± 149 seconds; P = .05) were needed in the PM group using the proposed protocol. Global clinical success reached 87% for the PM group and 90% (P = .58) the for LAT mapping group.
Conclusion
When LAT mapping is precluded, application of a PM-guided ablation protocol directed to >94% matching correlation target area is a more efficient alternative with comparable clinical results.
ed to >94% matching correlation target area is a more efficient alternative with comparable clinical results.
Idioma: Inglés
DOI: 10.1016/j.hrthm.2021.05.023
Año: 2021
Publicado en: HEART RHYTHM 18, 10 (2021), 1709-1716
ISSN: 1547-5271
Factor impacto JCR: 6.779 (2021)
Categ. JCR: CARDIAC & CARDIOVASCULAR SYSTEMS rank: 36 / 143 = 0.252 (2021) - Q2 - T1
Factor impacto CITESCORE: 10.1 - Medicine (Q1)
Factor impacto SCIMAGO: 2.402 - Physiology (medical) (Q1) - Cardiology and Cardiovascular Medicine (Q1)
Tipo y forma: Artículo (PostPrint)
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Exportado de SIDERAL (2026-01-07-18:53:13)
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Pacemapping (PM) is a useful maneuver for aiding premature ventricular complex (PVC) ablation. Its standalone clinical value is still to be defined.
Objectives
The purpose of this study was to analyze the efficacy of a predefined PM protocol for low-burden PVC ablation, regardless of their site of origin (SOO) and the presence of structural heart disease.
Methods
This was a prospective, nonrandomized, multicenter study. The PM protocol was performed when <1 PVC/min was found. The “target area” was delimited by the 3 best matching points >94% correlation, and 3 radiofreqency (RF) applications were delivered.
Results
Of 185 patients, 105 (57%) underwent activation mapping, 60 (32%) were PM-guided, and 20 (11%) were canceled due to absence of PVCs. Baseline QRS, PVC burden, and outflow tract origin were independent predictors of PM-guided ablation. A higher proportion of right ventricular outflow tract SOO in the PM group (52% vs 40%; P = .03) was observed. Mean target area was 0.6 ± 0.9 cm2. Mean 10-ms isochronal area in local activation time (LAT)-guided procedures was higher (1.7 ± 2.3 cm2; P <.001). Mean number of PM matching points acquired was 39 ± 21 (range 6–98). Mean mapping and RF times were similar in both groups. However, significantly shorter procedural (53 ± 24 vs 61 ± 26 minutes; P = .04) as well as RF times (111 ± 51 vs 149 ± 149 seconds; P = .05) were needed in the PM group using the proposed protocol. Global clinical success reached 87% for the PM group and 90% (P = .58) the for LAT mapping group.
Conclusion
When LAT mapping is precluded, application of a PM-guided ablation protocol directed to >94% matching correlation target area is a more efficient alternative with comparable clinical results.
ed to >94% matching correlation target area is a more efficient alternative with comparable clinical results.
Idioma: Inglés
DOI: 10.1016/j.hrthm.2021.05.023
Año: 2021
Publicado en: HEART RHYTHM 18, 10 (2021), 1709-1716
ISSN: 1547-5271
Factor impacto JCR: 6.779 (2021)
Categ. JCR: CARDIAC & CARDIOVASCULAR SYSTEMS rank: 36 / 143 = 0.252 (2021) - Q2 - T1
Factor impacto CITESCORE: 10.1 - Medicine (Q1)
Factor impacto SCIMAGO: 2.402 - Physiology (medical) (Q1) - Cardiology and Cardiovascular Medicine (Q1)
Tipo y forma: Artículo (PostPrint)
Debe reconocer adecuadamente la autoría, proporcionar un enlace a la licencia e indicar si se han realizado cambios. Puede hacerlo de cualquier manera razonable, pero no de una manera que sugiera que tiene el apoyo del licenciador o lo recibe por el uso que hace. No puede utilizar el material para una finalidad comercial. Si remezcla, transforma o crea a partir del material, no puede difundir el material modificado.Exportado de SIDERAL (2026-01-07-18:53:13)
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Registro creado el 2026-01-07, última modificación el 2026-01-07