165365 20260107201858.0 doi 10.1016/j.hrthm.2021.05.023 sideral 146814 ART-2021-146814 eng B, Jáuregui (orcid)0000-0001-9187-1773 Impact of a Pre-defined Pacemapping Protocol Use for Ablation of Infrequent Premature Ventricular Complexes: A Prospective, Multicenter Study. 2021 Background Pacemapping (PM) is a useful maneuver for aiding premature ventricular complex (PVC) ablation. Its standalone clinical value is still to be defined. Objectives The purpose of this study was to analyze the efficacy of a predefined PM protocol for low-burden PVC ablation, regardless of their site of origin (SOO) and the presence of structural heart disease. Methods This was a prospective, nonrandomized, multicenter study. The PM protocol was performed when <1 PVC/min was found. The “target area” was delimited by the 3 best matching points >94% correlation, and 3 radiofreqency (RF) applications were delivered. Results Of 185 patients, 105 (57%) underwent activation mapping, 60 (32%) were PM-guided, and 20 (11%) were canceled due to absence of PVCs. Baseline QRS, PVC burden, and outflow tract origin were independent predictors of PM-guided ablation. A higher proportion of right ventricular outflow tract SOO in the PM group (52% vs 40%; P = .03) was observed. Mean target area was 0.6 ± 0.9 cm2. Mean 10-ms isochronal area in local activation time (LAT)-guided procedures was higher (1.7 ± 2.3 cm2; P <.001). Mean number of PM matching points acquired was 39 ± 21 (range 6–98). Mean mapping and RF times were similar in both groups. However, significantly shorter procedural (53 ± 24 vs 61 ± 26 minutes; P = .04) as well as RF times (111 ± 51 vs 149 ± 149 seconds; P = .05) were needed in the PM group using the proposed protocol. Global clinical success reached 87% for the PM group and 90% (P = .58) the for LAT mapping group. Conclusion When LAT mapping is precluded, application of a PM-guided ablation protocol directed to >94% matching correlation target area is a more efficient alternative with comparable clinical results. ed to >94% matching correlation target area is a more efficient alternative with comparable clinical results. Access copy available to the general public Unrestricted info:eu-repo/semantics/openAccess by-nc-nd https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es 6.779 2021 CARDIAC & CARDIOVASCULAR SYSTEMS 36 / 143 = 0.252 2021 Q2 T1 2.402 2021 Physiology (medical) 2021 Q1 Cardiology and Cardiovascular Medicine 2021 Q1 10.1 2021 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion D, Penela J, Fernández-Armenta J, Acosta C, Terés D, Soto-Iglesias E, Silva A, Ordóñez Antonio R, San A, Chauca JM, Carreño C, Scherer A, Berruezo 18, 10 (2021), 1709-1716 Heart Rhythm HEART RHYTHM 1547-5271 683951 http://zaguan.unizar.es/record/165365/files/texto_completo.pdf Postprint 1148441 http://zaguan.unizar.es/record/165365/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:165365 articulos driver 2026-01-07-18:53:13 ARTICLE