165394 20260107201858.0 doi 10.3390/jcm15010101 sideral 147056 ART-2025-147056 eng Ioakeim-Sokoufa, Ignatios Universidad de Zaragoza Multimorbidity in Focus: Emerging Patterns, Medication Appropriateness and Clinical Innovation 2025 Chronic conditions and multimorbidity are significantly altering the landscape of modern clinical care. When we launched this Special Issue, our goal was to compile research that sheds light on these challenges from various perspectives, including clinical, epidemiological, methodological and patient-centred. This Special Issue provides insights into disease trajectories, medication safety, vulnerable populations and emerging tools to understand and address multimorbidity, such as artificial intelligence (AI). We are grateful to all the contributing authors, the reviewers who enhanced the manuscripts and the editorial team of the Journal of Clinical Medicine for their support in this endeavour. Recent advancements in medicine and technology have improved the survival and management of chronic conditions. Multimorbidity has now become a common clinical concern among adults of all ages, from the young population to people over 100 [1,2,3,4]. This epidemiological shift poses significant challenges for healthcare providers and national health and social care systems, where clinical guidelines mainly focus on single diseases, failing to consider a person-centred approach in the management of people with multiple chronic conditions. The contributions in this Special Issue collectively underline that multimorbidity is not a static construct but a dynamic process that evolves across life stages, involves clinical and pharmacological interactions, and requires a re-engineering of current models of care Access copy available to the general public Unrestricted info:eu-repo/semantics/openAccess by https://creativecommons.org/licenses/by/4.0/deed.es info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Aza-Pascual-Salcedo, Mercedes Coelho, Helena Vicente-Romero, Jorge 1012 315 Universidad de Zaragoza Dpto. Farmac.Fisiol.y Med.L.F. Área Farmacología 15, 1 (2025), 101 [6 pp.] J. clin.med. Journal of Clinical Medicine 2077-0383 188672 http://zaguan.unizar.es/record/165394/files/texto_completo.pdf Versión publicada 2537754 http://zaguan.unizar.es/record/165394/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:165394 articulos driver 2026-01-07-18:53:46 ARTICLE