165405 20260108143203.0 doi 10.1182/blood-2017-07-795302 sideral 101907 ART-2017-101907 eng Salar, Antonio Long-term results of a phase 2 study of rituximab and bendamustine for mucosa-associated lymphoid tissue lymphoma 2017 To the editor: Extranodal marginal zone B-cell lymphomas of mucosa-associated lymphoid tissue (MALT) present in most cases as localized disease and can be successfully treated with local therapies or antibiotics.1¿¿-4 Moreover, patients with multicentric or extensive disease or relapsed disease may require systemic treatment with chemotherapy and/or rituximab.5¿¿-8 Also, considering the relative frequency of late relapses9 and that extragastric MALT lymphomas have an increased relapse risk, 10 systemic treatment has also been used in the first-line setting. Several chemotherapy agents, anti-CD20 monoclonal antibodies, immunomodulatory agents, and their combinations have been demonstrated to be effective specifically in MALT lymphomas.11¿¿-14 Herewith, we report the long-term results of the MALT 2008-01 phase 2 trial15 using a response-adapted protocol with the combination of rituximab and bendamustine (RB) as first-line treatment of MALT lymphomas after a median follow-up of 7 years. This trial was registered at www.clinicaltrials.gov as #NCT01015248 and in EudraCT as #2008-007725-39.... info:eu-repo/semantics/closedAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 15.132 2017 HEMATOLOGY 2 / 71 = 0.028 2017 Q1 T1 6.434 2017 Biochemistry 2017 Q1 Immunology 2017 Q1 Hematology 2017 Q1 Cell Biology 2017 Q1 info:eu-repo/semantics/other info:eu-repo/semantics/publishedVersion Domingo-Domenech, Eva Panizo, Carlos Nicolás, Concepción Bargay, Joan Muntañola, Ana Canales, Miguel Bello, José Luis Sancho, Juan Manuel Tomás, José Francisco Rodríguez, María José Peñalver, Javier Grande, Carlos Sánchez-Blanco, José Javier Palomera, Luis Universidad de Zaragoza (orcid)0000-0001-8515-3599 Arranz, Reyes Conde, Eulogio García, Mar (orcid)0000-0003-2078-8205 García, Juan Fernando Caballero, Dolores Montalbán, Carlos 1007 610 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Medicina 130, 15 (2017), 1772-1774 Blood Blood 0006-4971 579491 http://zaguan.unizar.es/record/165405/files/texto_completo.pdf Versión publicada 3670375 http://zaguan.unizar.es/record/165405/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:165405 articulos driver 2026-01-08-14:09:58 ARTICLE