165433 20260108143204.0 doi 10.1016/S0140-6736(12)61148-9 sideral 118423 ART-2012-118423 eng Pearse, Rupert M. Mortality after surgery in Europe: a 7 day cohort study 2012 Background Clinical outcomes after major surgery are poorly described at the national level. Evidence of heterogeneity between hospitals and health-care systems suggests potential to improve care for patients but this potential remains unconfirmed. The European Surgical Outcomes Study was an international study designed to assess outcomes after non-cardiac surgery in Europe. Methods We did this 7 day cohort study between April 4 and April 11, 2011. We collected data describing consecutive patients aged 16 years and older undergoing inpatient non-cardiac surgery in 498 hospitals across 28 European nations. Patients were followed up for a maximum of 60 days. The primary endpoint was in-hospital mortality. Secondary outcome measures were duration of hospital stay and admission to critical care. We used χ2 and Fisher's exact tests to compare categorical variables and the t test or the Mann-Whitney U test to compare continuous variables. Significance was set at p<0·05. We constructed multilevel logistic regression models to adjust for the differences in mortality rates between countries. Findings We included 46 539 patients, of whom 1855 (4%) died before hospital discharge. 3599 (8%) patients were admitted to critical care after surgery with a median length of stay of 1·2 days (IQR 0·9–3·6). 1358 (73%) patients who died were not admitted to critical care at any stage after surgery. Crude mortality rates varied widely between countries (from 1·2% [95% CI 0·0–3·0] for Iceland to 21·5% [16·9–26·2] for Latvia). After adjustment for confounding variables, important differences remained between countries when compared with the UK, the country with the largest dataset (OR range from 0·44 [95% CI 0·19–1·05; p=0·06] for Finland to 6·92 [2·37–20·27; p=0·0004] for Poland). Interpretation The mortality rate for patients undergoing inpatient non-cardiac surgery was higher than anticipated. Variations in mortality between countries suggest the need for national and international strategies to improve care for this group of patients. Access copy available to the general public Unrestricted info:eu-repo/semantics/openAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 39.06 2012 MEDICINE, GENERAL & INTERNAL 2 / 153 = 0.013 2012 Q1 T1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Moreno, Rui P. Bauer, Peter Pelosi, Paolo Metnitz, Philipp Spies, Claudia Benoit Vallet, Benoit Vincent, Jean-Louis Hoeft, Andreas Rhodes, Andrew Serón Arbeloa, Carlos Universidad de Zaragoza (orcid)0000-0002-8068-5016 for the European Surgical Outcomes Study (EuSOS) group for the Trials groups of the European Society of Intensive Care Medicine and the European Society of Anaesthesiology* 1007 610 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Medicina 380, 9847 (2012), 1059-65 Lancet The Lancet 0140-6736 286402 http://zaguan.unizar.es/record/165433/files/texto_completo.pdf Versión publicada 3251492 http://zaguan.unizar.es/record/165433/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:165433 articulos driver 2026-01-08-14:10:32 ARTICLE