165450 20260108143204.0 sideral 147049 ART-2017-147049 eng Olivera Pueyo, Francisco Javier Universidad de Zaragoza (orcid)0000-0001-9243-0339 Dietary supplements for cognitive impairment 2017 Alzheimer disease and the other neurodegenerative dementias as yet have no curative treatment. For this reason, the prevention of these conditions and non-pharmacological treatments are important fields of research at present. The Mediterranean diet (rich in fruits, vegetables, legumes, and olive oil, with regular fish consumption and low consumption of dairy products and meats) has been shown to reduce the incidence of mild cognitive impairment (MCI) and, probably, the conversion of MCI to dementia. Vitamins, especially vitamin E and the vitamins of the B group, have also been associated with the prevention of cognitive impairment due to their antioxidant effects. Ginkgo biloba is one of the most widely used supplements in the world for cognitive improvement because of its possible effects as a vasodilator and facilitator of cerebral vascularization. Green tea polyphenols have shown beneficial effects in different diseases, including cognitive impairment. Cerebral aging is associated with changes in the lipid composition of neuronal membranes, so it has been suggested that treatment with phospholipids like phosphatidylcholine and phosphatidylserine could favor cognitive improvement. Similarly, polyunsaturated and omega-3 fatty acids, and docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) supplements are associated with a beneficial effect on cognitive function due to the cumulative summation of factors that ultimately favor membrane permeability and neuronal functioning. Issue Vol. 45 No. Suppl. 1 (2017) Section Original Access copy available to the general public Unrestricted info:eu-repo/semantics/openAccess by https://creativecommons.org/licenses/by/4.0/deed.es 0.878 2017 PSYCHIATRY 123 / 141 = 0.872 2017 Q4 T3 NEUROSCIENCES 243 / 261 = 0.931 2017 Q4 T3 0.333 2017 Psychiatry and Mental Health 2017 Q3 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Pelegrín Valero, Carmelo Universidad de Zaragoza (orcid)0000-0002-4036-4541 1007 745 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Psiquiatría 45, Suppl. 1 (2017), 37 - 47 Actas esp. psiquiatr. Actas españolas de psiquiatría 1139-9287 88705 http://zaguan.unizar.es/record/165450/files/texto_completo.pdf Versión publicada 2113596 http://zaguan.unizar.es/record/165450/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:165450 articulos driver 2026-01-08-14:10:50 ARTICLE