000165457 001__ 165457 000165457 005__ 20260108143204.0 000165457 0247_ $$2doi$$a10.23938/ASSN.1136 000165457 0248_ $$2sideral$$a147028 000165457 037__ $$aART-2025-147028 000165457 041__ $$aeng 000165457 100__ $$0(orcid)0000-0002-0061-3312$$aGómez-Soria, I.$$uUniversidad de Zaragoza 000165457 245__ $$aDifferential effects of computerized cognitive stimulation versus stimulating leisure activities on mood and global cognition in adults with subjective and mild cognitive impairment: A randomized controlled trial 000165457 260__ $$c2025 000165457 5060_ $$aAccess copy available to the general public$$fUnrestricted 000165457 5203_ $$aBackground. Mild Cognitive Impairment (MCI) involves both subjective and objective cognitive decline with relatively preserved daily functioning, whereas Subjective Cognitive Impairment (SCI) refers to perceived decline without measurable deficits. This study aimed to compare the effects of a personalized computerized cognitive stimulation (CS) program (IG1) and a stimulating leisure activities program (IG2) in adults with MCI and SCI. Methods. A single-blind randomized controlled trial was conducted in primary care with participants aged ≥50 years with SCI or MCI. Participants were randomized to IG1, IG2), or a control group (CG). IG1 completed personalized computerized CS for 30 minutes/day, 5 days/week, for 8 weeks. IG2 engaged in 2-5 stimulating leisure activities per week for the same period. The primary outcome was global cognition; secondary outcomes included memory, verbal fluency, daily functioning, and mood. Results. Fifty-nine participants were enrolled in the study, 44 with SCI and 15 with MCI. Compared to CG, IG1 showed greater reductions in anxiety post-intervention (2.07; 95%CI: 0.93-3.22 vs. 4.34; 95%CI: 3.22-5.46) and lower depressive symptoms at 6-month follow-up (3.41; 95%CI: 2.05-4.77 vs. 5.62; 95%CI: 4.26-6.97). IG2 participants demonstrated improved global cognition post-intervention (29.2; 95%CI: 27.625-30.776) and at 6 months (28.78; 95%CI: 27.16- 30.42) relative to CG (30.626; 95%CI: 28.99-32.27). Conclusion. Personalized computerized CS reduces anxiety and depression symptoms, while stimulating leisure activities enhances global cognition in community-dwelling adults with SCI and MCI, suggesting complementary benefits of both interventions. Keywords. Mild Cognitive Impairment. Subjective Cognitive Impairment. Computerized Cognitive Stimulation. Stimulating Leisure Activities. Primary Care 000165457 536__ $$9info:eu-repo/grantAgreement/ES/DGA/B21-23R-GAIAP 000165457 540__ $$9info:eu-repo/semantics/openAccess$$aby-sa$$uhttps://creativecommons.org/licenses/by-sa/4.0/deed.es 000165457 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000165457 700__ $$aCuenca-Zaldivar, J. N. 000165457 700__ $$0(orcid)0000-0001-6565-9699$$aOliván-Blázquez, B.$$uUniversidad de Zaragoza 000165457 700__ $$0(orcid)0000-0003-2683-7346$$aAguilar Latorre, A.$$uUniversidad de Zaragoza 000165457 700__ $$0(orcid)0000-0002-5494-6550$$aMagallón-Botaya, R. M.,$$uUniversidad de Zaragoza 000165457 700__ $$0(orcid)0000-0002-4307-796X$$aCalatayud, E.$$uUniversidad de Zaragoza 000165457 7102_ $$14009$$2740$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Psicología Social 000165457 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina 000165457 7102_ $$11006$$2413$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Fisioterapia 000165457 7102_ $$14009$$2735$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Psicolog.Evolut.Educac 000165457 773__ $$g48, 3 (2025), e1136$$pAn. sist. sanit. Navar.$$tAnales del Sistema Sanitario de Navarra$$x1137-6627 000165457 8564_ $$s686525$$uhttps://zaguan.unizar.es/record/165457/files/texto_completo.pdf$$yVersión publicada 000165457 8564_ $$s3320947$$uhttps://zaguan.unizar.es/record/165457/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000165457 909CO $$ooai:zaguan.unizar.es:165457$$particulos$$pdriver 000165457 951__ $$a2026-01-08-14:10:58 000165457 980__ $$aARTICLE