000165492 001__ 165492 000165492 005__ 20260112132214.0 000165492 0247_ $$2doi$$a10.1016/J.SMALLRUMRES.2019.07.010 000165492 0248_ $$2sideral$$a114618 000165492 037__ $$aART-2019-114618 000165492 041__ $$aeng 000165492 100__ $$0(orcid)0000-0002-4655-9171$$aGonzález, J.M.$$uUniversidad de Zaragoza 000165492 245__ $$aPrevention of Ovine Respiratory Complex in lambs based on vaccination 000165492 260__ $$c2019 000165492 5060_ $$aAccess copy available to the general public$$fUnrestricted 000165492 5203_ $$aVaccination programs against Ovine Respiratory Complex (ORC) in lambs should be accompanied by non-specific preventive measure, e.g., establishment of proper management and husbandry conditions. Implementing a vaccination plan against ORC requires: involvement of all farm staff, recording data, a positive cost:benefit analysis and continuous monitoring over time. Licensed vaccines for sheep are only against Mannheimia haemolytica (MH), Bibersteinia trehalosi (BT) and Pasteurella multocida (PM). According to the antigens contained in the MH vaccines, these can be divided into outer membrane protein vaccines (OmpA), leucotoxoid vaccines (LKT) and iron regulated protein vaccines (IROMP). Each serotype of MH or BT presents differences in these three antigens, although in the case of IROMP, there is an effective cross protection among them. In addition, strains of bovine origin do not protect sheep and vice versa. For PM, vaccines containing bacteria grown in iron restricted conditions give better results. The lambs should be vaccinated during the first week of life followed by a booster dose three weeks apart. The best results are obtained with LKT vaccines, when the serotype that is present in the farm is included in the vaccine, or with IROMP, which can be applied in any situation. 000165492 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es 000165492 590__ $$a1.273$$b2019 000165492 591__ $$aAGRICULTURE, DAIRY & ANIMAL SCIENCE$$b34 / 63 = 0.54$$c2019$$dQ3$$eT2 000165492 592__ $$a0.568$$b2019 000165492 593__ $$aFood Animals$$c2019$$dQ2 000165492 593__ $$aAnimal Science and Zoology$$c2019$$dQ2 000165492 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion 000165492 700__ $$0(orcid)0000-0002-4557-6033$$aNavarro, T.$$uUniversidad de Zaragoza 000165492 700__ $$0(orcid)0000-0002-7822-6646$$aLacasta, D.$$uUniversidad de Zaragoza 000165492 700__ $$0(orcid)0000-0002-2724-2785$$aRamos, J.J.$$uUniversidad de Zaragoza 000165492 700__ $$0(orcid)0000-0003-0042-8800$$aFerrer, L.M.$$uUniversidad de Zaragoza 000165492 700__ $$aVasileiou, N.G.C. 000165492 700__ $$0(orcid)0000-0003-3792-287X$$ade las Heras, M.$$uUniversidad de Zaragoza 000165492 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Sanidad Animal 000165492 7102_ $$11009$$2X$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cProy. investigación HRA 000165492 7102_ $$11009$$2617$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Medicina y Cirugía Animal 000165492 773__ $$g180 (2019), 127-130$$pSmall rumin. res.$$tSmall Ruminant Research$$x0921-4488 000165492 8564_ $$s331121$$uhttps://zaguan.unizar.es/record/165492/files/texto_completo.pdf$$yPostprint 000165492 8564_ $$s2086471$$uhttps://zaguan.unizar.es/record/165492/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint 000165492 909CO $$ooai:zaguan.unizar.es:165492$$particulos$$pdriver 000165492 951__ $$a2026-01-12-11:08:23 000165492 980__ $$aARTICLE