165492 20260112132214.0 doi 10.1016/J.SMALLRUMRES.2019.07.010 sideral 114618 ART-2019-114618 eng González, J.M. Universidad de Zaragoza (orcid)0000-0002-4655-9171 Prevention of Ovine Respiratory Complex in lambs based on vaccination 2019 Vaccination programs against Ovine Respiratory Complex (ORC) in lambs should be accompanied by non-specific preventive measure, e.g., establishment of proper management and husbandry conditions. Implementing a vaccination plan against ORC requires: involvement of all farm staff, recording data, a positive cost:benefit analysis and continuous monitoring over time. Licensed vaccines for sheep are only against Mannheimia haemolytica (MH), Bibersteinia trehalosi (BT) and Pasteurella multocida (PM). According to the antigens contained in the MH vaccines, these can be divided into outer membrane protein vaccines (OmpA), leucotoxoid vaccines (LKT) and iron regulated protein vaccines (IROMP). Each serotype of MH or BT presents differences in these three antigens, although in the case of IROMP, there is an effective cross protection among them. In addition, strains of bovine origin do not protect sheep and vice versa. For PM, vaccines containing bacteria grown in iron restricted conditions give better results. The lambs should be vaccinated during the first week of life followed by a booster dose three weeks apart. The best results are obtained with LKT vaccines, when the serotype that is present in the farm is included in the vaccine, or with IROMP, which can be applied in any situation. Access copy available to the general public Unrestricted info:eu-repo/semantics/openAccess by-nc-nd https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es 1.273 2019 AGRICULTURE, DAIRY & ANIMAL SCIENCE 34 / 63 = 0.54 2019 Q3 T2 0.568 2019 Food Animals 2019 Q2 Animal Science and Zoology 2019 Q2 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Navarro, T. Universidad de Zaragoza (orcid)0000-0002-4557-6033 Lacasta, D. Universidad de Zaragoza (orcid)0000-0002-7822-6646 Ramos, J.J. Universidad de Zaragoza (orcid)0000-0002-2724-2785 Ferrer, L.M. Universidad de Zaragoza (orcid)0000-0003-0042-8800 Vasileiou, N.G.C. de las Heras, M. Universidad de Zaragoza (orcid)0000-0003-3792-287X 1009 773 Universidad de Zaragoza Dpto. Patología Animal Área Sanidad Animal 1009 X Universidad de Zaragoza Dpto. Patología Animal Proy. investigación HRA 1009 617 Universidad de Zaragoza Dpto. Patología Animal Área Medicina y Cirugía Animal 180 (2019), 127-130 Small rumin. res. Small Ruminant Research 0921-4488 331121 http://zaguan.unizar.es/record/165492/files/texto_completo.pdf Postprint 2086471 http://zaguan.unizar.es/record/165492/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:165492 articulos driver 2026-01-12-11:08:23 ARTICLE