000165656 001__ 165656
000165656 005__ 20260114125841.0
000165656 0247_ $$2doi$$a10.1515/dmpt-2018-0017
000165656 0248_ $$2sideral$$a109091
000165656 037__ $$aART-2018-109091
000165656 041__ $$aeng
000165656 100__ $$aRodríguez Vicente, A.E.
000165656 245__ $$aPersonalized medicine into health national services: Barriers and potentialities
000165656 260__ $$c2018
000165656 5060_ $$aAccess copy available to the general public$$fUnrestricted
000165656 5203_ $$aResearch and innovation in personalized medicine (PM) are extensive and expanding, with several pharmacogenetic/pharmacogenomic (PGx) testing options currently available for a wide range of health problems. However, PGx-guided therapy faces many barriers to full integration into clinical practice and acceptance by practitioner/patient: utilization and uptake by payers in real-world practice are being discussed, and the criteria to guide clinicians and policy makers in PGx test selection are not fully incorporated. This review focuses on the advances of pharmacogenomics to individualize treatments, the relationship between pharmacogenetics and pharmacometabolomics, the new paradigm of the Big Data, the needs and barriers facing PGx clinical application and the situation of PGx testing in health national services. It is based on lectures presented by speakers of the European Society of Pharmacogenomics and Personalised Therapy (ESPT) Fourth Conference, held in Catania, October 4th, 2017.
000165656 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttps://creativecommons.org/licenses/by-nc/4.0/deed.es
000165656 592__ $$a0.277$$b2018
000165656 593__ $$aPharmacology, Toxicology and Pharmaceutics (miscellaneous)$$c2018$$dQ2
000165656 593__ $$aPharmacology (medical)$$c2018$$dQ2
000165656 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000165656 700__ $$aHerrero Cervera, M.J.
000165656 700__ $$0(orcid)0000-0002-8222-1418$$aBernal, M.L.$$uUniversidad de Zaragoza
000165656 700__ $$aRojas, L.
000165656 700__ $$aPeiró, A.M.
000165656 7102_ $$11005$$2315$$aUniversidad de Zaragoza$$bDpto. Farmacología y Fisiolog.$$cÁrea Farmacología
000165656 773__ $$g33, 4 (2018), 159-163$$pDrug metab. person. ther.$$tDrug metabolism and personalized therapy$$x2363-8907
000165656 8564_ $$s162395$$uhttps://zaguan.unizar.es/record/165656/files/texto_completo.pdf$$yPostprint
000165656 8564_ $$s2761160$$uhttps://zaguan.unizar.es/record/165656/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000165656 909CO $$ooai:zaguan.unizar.es:165656$$particulos$$pdriver
000165656 951__ $$a2026-01-14-12:57:59
000165656 980__ $$aARTICLE