165656 20260114125841.0 doi 10.1515/dmpt-2018-0017 sideral 109091 ART-2018-109091 eng Rodríguez Vicente, A.E. Personalized medicine into health national services: Barriers and potentialities 2018 Access copy available to the general public Unrestricted Research and innovation in personalized medicine (PM) are extensive and expanding, with several pharmacogenetic/pharmacogenomic (PGx) testing options currently available for a wide range of health problems. However, PGx-guided therapy faces many barriers to full integration into clinical practice and acceptance by practitioner/patient: utilization and uptake by payers in real-world practice are being discussed, and the criteria to guide clinicians and policy makers in PGx test selection are not fully incorporated. This review focuses on the advances of pharmacogenomics to individualize treatments, the relationship between pharmacogenetics and pharmacometabolomics, the new paradigm of the Big Data, the needs and barriers facing PGx clinical application and the situation of PGx testing in health national services. It is based on lectures presented by speakers of the European Society of Pharmacogenomics and Personalised Therapy (ESPT) Fourth Conference, held in Catania, October 4th, 2017. info:eu-repo/semantics/openAccess by-nc https://creativecommons.org/licenses/by-nc/4.0/deed.es 0.277 2018 Pharmacology, Toxicology and Pharmaceutics (miscellaneous) 2018 Q2 Pharmacology (medical) 2018 Q2 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Herrero Cervera, M.J. Bernal, M.L. Universidad de Zaragoza (orcid)0000-0002-8222-1418 Rojas, L. Peiró, A.M. 1005 315 Universidad de Zaragoza Dpto. Farmacología y Fisiolog. Área Farmacología 33, 4 (2018), 159-163 Drug metab. person. ther. Drug metabolism and personalized therapy 2363-8907 162395 http://zaguan.unizar.es/record/165656/files/texto_completo.pdf Postprint 2761160 http://zaguan.unizar.es/record/165656/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:165656 articulos driver 2026-01-14-12:57:59 ARTICLE