165752 20260204133827.0 sideral 70900 ART-2010-70900 eng Conesa, C. (orcid)0000-0003-0862-9893 Recombinant human lactoferrin: A valuable protein for pharmaceutical products and functional foods 2010 Access copy available to the general public Unrestricted Lactoferrin, the main iron-binding protein of milk, has biological activities that are essential for the newborn and are beneficial for adults. Given this beneficial effect, there is broad interest in exogenous sources of lactoferrin in human nutrition. Consequently, several transgenic approaches to produce lactoferrin have been achieved. However, the activity of heterologous lactoferrin cannot be assumed to identically mimic that of the homologous protein. Human lactoferrin obtained from yeast, transgenic cows, and rice has met the criteria of structural similarity, high yield, and ease of protein isolation. Human lactoferrin from Aspergillus awamori has been mainly directed to therapeutic uses with advanced phases of clinical trials currently in progress. In contrast, human lactoferrin produced in transgenic cows and rice brings the clear advantage of origins compatible with use in foods, although the approval for these applications is still in process. info:eu-repo/semantics/openAccess by-nc-nd https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es 7.6 2010 BIOTECHNOLOGY & APPLIED MICROBIOLOGY 9 / 158 = 0.057 2010 Q1 T1 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Calvo, M. Universidad de Zaragoza (orcid)0000-0001-5373-9210 Sanchez, L. Universidad de Zaragoza (orcid)0000-0001-5964-823X 2008 780 Universidad de Zaragoza Dpto. Produc.Animal Cienc.Ali. Área Tecnología de Alimentos 28, 6 (2010), 831-838 Biotechnol. adv. BIOTECHNOLOGY ADVANCES 0734-9750 906222 http://zaguan.unizar.es/record/165752/files/texto_completo.pdf Postprint 544582 http://zaguan.unizar.es/record/165752/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:165752 articulos driver 2026-02-04-13:18:09 ARTICLE