000165797 001__ 165797
000165797 005__ 20260114135812.0
000165797 0247_ $$2doi$$a10.1016/j.abb.2021.108770
000165797 0248_ $$2sideral$$a123158
000165797 037__ $$aART-2021-123158
000165797 041__ $$aeng
000165797 100__ $$0(orcid)0000-0001-6435-3540$$aSevilla, E.$$uUniversidad de Zaragoza
000165797 245__ $$aFur-like proteins: Beyond the ferric uptake regulator (Fur) paralog
000165797 260__ $$c2021
000165797 5060_ $$aAccess copy available to the general public$$fUnrestricted
000165797 5203_ $$aProteins belonging to the FUR (ferric uptake regulator) family are the cornerstone of metalloregulation in most prokaryotes. Although numerous reviews have been devoted to these proteins, these reports are mainly focused on the Fur paralog that gives name to the family. In the last years, the increasing knowledge on the other, less ubiquitous members of this family has evidenced their importance in bacterial metabolism. As the Fur paralog, the major regulator of iron homeostasis, Zur, Irr, BosR and PerR are tightly related to stress defenses and host-pathogen interaction being in many cases essential for virulence. Furthermore, the Nur and Mur paralogs largely contribute to control nickel and manganese homeostasis, which are cofactors of pivotal proteins for host colonization and bacterial redox homeostasis. The present review highlights the main features of FUR proteins that differ to the canonical Fur paralog either in the coregulatory metal, such as Zur, Nur and Mur, or in the action mechanism to control target genes, such as PerR, Irr and BosR.
000165797 536__ $$9info:eu-repo/grantAgreement/ES/DGA/E35-17R$$9info:eu-repo/grantAgreement/ES/MCIU/PID2019-104889GB-I00$$9info:eu-repo/grantAgreement/ES/MINECO/BFU2016-77671-P
000165797 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000165797 590__ $$a4.114$$b2021
000165797 591__ $$aBIOPHYSICS$$b24 / 71 = 0.338$$c2021$$dQ2$$eT2
000165797 591__ $$aBIOCHEMISTRY & MOLECULAR BIOLOGY$$b155 / 297 = 0.522$$c2021$$dQ3$$eT2
000165797 592__ $$a0.826$$b2021
000165797 593__ $$aBiophysics$$c2021$$dQ1
000165797 593__ $$aBiochemistry$$c2021$$dQ1
000165797 594__ $$a6.7$$b2021
000165797 655_4 $$ainfo:eu-repo/semantics/review$$vinfo:eu-repo/semantics/publishedVersion
000165797 700__ $$0(orcid)0000-0002-8181-2689$$aBes, M.T.$$uUniversidad de Zaragoza
000165797 700__ $$0(orcid)0000-0002-2742-3711$$aPeleato, M.L.$$uUniversidad de Zaragoza
000165797 700__ $$0(orcid)0000-0001-8644-4574$$aFillat, M.F.$$uUniversidad de Zaragoza
000165797 7102_ $$11002$$2412$$aUniversidad de Zaragoza$$bDpto. Bioq.Biolog.Mol. Celular$$cÁrea Fisiología Vegetal
000165797 7102_ $$11002$$2060$$aUniversidad de Zaragoza$$bDpto. Bioq.Biolog.Mol. Celular$$cÁrea Bioquímica y Biolog.Mole.
000165797 773__ $$g701 (2021), 108770 [16 pp]$$pArch. biochem. biophys.$$tARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS$$x0003-9861
000165797 8564_ $$s6183089$$uhttps://zaguan.unizar.es/record/165797/files/texto_completo.pdf$$yVersión publicada
000165797 8564_ $$s2686641$$uhttps://zaguan.unizar.es/record/165797/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000165797 909CO $$ooai:zaguan.unizar.es:165797$$particulos$$pdriver
000165797 951__ $$a2026-01-14-12:45:58
000165797 980__ $$aARTICLE