000165839 001__ 165839 000165839 005__ 20260115140311.0 000165839 0247_ $$2doi$$a10.1038/s41433-020-0859-3 000165839 0248_ $$2sideral$$a117601 000165839 037__ $$aART-2020-117601 000165839 041__ $$aeng 000165839 100__ $$aMansour, A.M. 000165839 245__ $$aPrepapillary vascular loop-a new classification 000165839 260__ $$c2020 000165839 5060_ $$aAccess copy available to the general public$$fUnrestricted 000165839 5203_ $$aBackground/Objectives: To analyze the ophthalmic characteristics of congenital prepapillary vascular loop (PVL) and to propose a new morphologic classification dividing the loops into six types. Subjects/Methods: Collaborative multinational multicentre retrospective study of PVL cases. Results: There was a total of 49 cases (61 eyes), 37 unilateral (75.5%) and 12 bilateral (24.5%), 32 arterial type (65.3%) and 18 venous type (36.7%) (one patient had either kind in each eye). The mean number of loops per eye was 2.7 (range, 1–7). The loops were asymptomatic in 42 cases (85.7%). Other findings included: the presence of cilioretinal artery (14 cases), retinal vascular tortuosity (26 cases), amaurosis fugax (1 case), branch retinal artery occlusion (1 case) and vitreous haemorrhage (3 cases). Six morphologic loop types could be discerned based on elevation (flat vs. elevated), shape (figure of 8 or corkscrew with hyaline sheath), number (multiple or single), location (central or peripheral), lumen size (arterial vs. arteriolar) and presence of vascular tortuosity or vitreous traction. Conclusions: PVL are usually asymptomatic and can be divided into six morphologic types with different pathogenesis during early embryogenesis. 000165839 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/ 000165839 590__ $$a3.775$$b2020 000165839 591__ $$aOPHTHALMOLOGY$$b12 / 62 = 0.194$$c2020$$dQ1$$eT1 000165839 592__ $$a1.446$$b2020 000165839 593__ $$aArts and Humanities (miscellaneous)$$c2020$$dQ1 000165839 593__ $$aSensory Systems$$c2020$$dQ1 000165839 593__ $$aOphthalmology$$c2020$$dQ1 000165839 593__ $$aMedicine (miscellaneous)$$c2020$$dQ1 000165839 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion 000165839 700__ $$aKozak, I. 000165839 700__ $$aSaatci, A.O. 000165839 700__ $$0(orcid)0000-0001-9876-5850$$aAscaso, F.J.$$uUniversidad de Zaragoza 000165839 700__ $$aBroc, L. 000165839 700__ $$aBattaglia, M. 000165839 700__ $$aOlivier, N. 000165839 700__ $$aGili, P. 000165839 700__ $$aChhablani, J. 000165839 700__ $$aHedges, T.R. 000165839 700__ $$aHonrubia, A. 000165839 700__ $$aGutierrez, L. 000165839 700__ $$aPanozzo, G. 000165839 700__ $$aCatalà, J. 000165839 700__ $$aDíaz, J. 000165839 700__ $$aCarreras, E. 000165839 700__ $$aKadayifcilar, S. 000165839 700__ $$aAl Kahtani, E.S. 000165839 700__ $$aUwaydat, S.H. 000165839 700__ $$aLima, L.H. 000165839 700__ $$aMansour, H.A. 000165839 700__ $$aKhan, H.A. 000165839 700__ $$aAaberg, T.M. 000165839 700__ $$aJr 000165839 700__ $$aBovino, J.A. 000165839 700__ $$aHunyor, A.P. 000165839 7102_ $$11013$$2646$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Oftalmología 000165839 773__ $$g35 (2020), 425–432$$pEye$$tEye (Basingstoke)$$x0950-222X 000165839 8564_ $$s1824084$$uhttps://zaguan.unizar.es/record/165839/files/texto_completo.pdf$$yPostprint 000165839 8564_ $$s2417683$$uhttps://zaguan.unizar.es/record/165839/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint 000165839 909CO $$ooai:zaguan.unizar.es:165839$$particulos$$pdriver 000165839 951__ $$a2026-01-15-12:36:25 000165839 980__ $$aARTICLE