000165847 001__ 165847
000165847 005__ 20260115140311.0
000165847 0247_ $$2doi$$a10.1136/bjophthalmol-2021-319001
000165847 0248_ $$2sideral$$a126306
000165847 037__ $$aART-2021-126306
000165847 041__ $$aeng
000165847 100__ $$aUwaydat S.H.
000165847 245__ $$aClinical characteristics of full thickness macular holes that closed without surgery
000165847 260__ $$c2021
000165847 5060_ $$aAccess copy available to the general public$$fUnrestricted
000165847 5203_ $$aPurpose: To ascertain the anatomic factors that help achieve non-surgical sealing in full thickness macular hole (FTMH). Methods: Retrospective collaborative study of FTMH that closed without surgical intervention. Results: A total of 78 patients (mean age 57.9 years) included 18 patients with blunt ocular trauma, 18 patients that received topical or intravitreal therapies and 42 patients with idiopathic FTMH. Mean±SD of the initial corrected visual acuity (VA) in logMAR improved from 0.65±0.54 to 0.34±0.45 (p<0.001) at a mean follow-up of 33.8±37.1 months. FTMH reopened in seven eyes (9.0%) after a mean of 8.6 months. Vitreomacular traction was noted in 12 eyes (15.8%), perifoveal posterior vitreous detachment in 42 (53.8%), foveal epiretinal membrane in 10 (12.8%), cystoid macular oedema (CME) in 49 (62.8%) and subretinal fluid (SRF) in 20 (25.6%). By multivariate analysis, initial VA correlated to the height (p<0.001) and narrowest diameter of the hole (p<0.001) while final VA correlated to the basal diameter (p<0.001). Time for closure of FTMH (median 2.8 months) correlated to the narrowest diameter (p<0.001) and the presence of SRF (p=0.001). Mean time for closure (in months) was 1.6 for eyes with trauma, 4.3 for eyes without trauma but with therapy for CME, 4.4 for eyes without trauma and without therapy in less than 200 µm in size and 24.7 for more than 200 µm. Conclusion: Our data suggest an observation period in new onset FTMH for non-surgical closure, in the setting of trauma, treatment of CME and size <200 µm. © Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.
000165847 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttps://creativecommons.org/licenses/by-nc/4.0/deed.es
000165847 590__ $$a5.907$$b2021
000165847 591__ $$aOPHTHALMOLOGY$$b7 / 62 = 0.113$$c2021$$dQ1$$eT1
000165847 592__ $$a1.8$$b2021
000165847 593__ $$aOphthalmology$$c2021$$dQ1
000165847 593__ $$aCellular and Molecular Neuroscience$$c2021$$dQ1
000165847 594__ $$a8.4$$b2021
000165847 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000165847 700__ $$aMansour A.
000165847 700__ $$0(orcid)0000-0001-9876-5850$$aAscaso F.J.$$uUniversidad de Zaragoza
000165847 700__ $$aParodi M.B.
000165847 700__ $$aFoster R.
000165847 700__ $$aSmiddy W.E.
000165847 700__ $$aSchwartz S.G.
000165847 700__ $$aCharbaji A.
000165847 700__ $$aBelotto S.
000165847 700__ $$aJürgens I.
000165847 700__ $$aMateo J.
000165847 700__ $$aEllabban A.A.
000165847 700__ $$aWu L.
000165847 700__ $$aFigueroa M.
000165847 700__ $$aOlivier Pascual N.
000165847 700__ $$aLima L.H.
000165847 700__ $$aAlsakran W.A.
000165847 700__ $$aCaliskan Kadayifcilar S.
000165847 700__ $$aSinawat S.
000165847 700__ $$aAssi A.
000165847 700__ $$aMansour H.A.
000165847 700__ $$aCasella A.M.
000165847 700__ $$aNavea A.
000165847 700__ $$aNeila E.R.
000165847 700__ $$aSaatci A.O.
000165847 700__ $$aGovindahari V.
000165847 700__ $$aEsteban Floria O.
000165847 700__ $$aAgarwal K.
000165847 700__ $$aBakkali El Bakkali I.
000165847 700__ $$aAlaman A.S.
000165847 700__ $$aLarripa S.F.
000165847 700__ $$aRey A.
000165847 700__ $$aPera P.
000165847 700__ $$aBruix L.
000165847 700__ $$aLopez-Guajardo L.
000165847 700__ $$aPérez-Salvador E.
000165847 700__ $$aLara Medina F.J.
000165847 700__ $$aHrisomalos F.N.
000165847 700__ $$aChhablani J.
000165847 700__ $$aArevalo J.F.
000165847 7102_ $$11013$$2646$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Oftalmología
000165847 773__ $$g106, 10 (2021), 1463–1468$$pBr. j. ophthalmol.$$tBritish Journal of Ophthalmology$$x0007-1161
000165847 8564_ $$s1139955$$uhttps://zaguan.unizar.es/record/165847/files/texto_completo.pdf$$yPostprint
000165847 8564_ $$s3089459$$uhttps://zaguan.unizar.es/record/165847/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000165847 909CO $$ooai:zaguan.unizar.es:165847$$particulos$$pdriver
000165847 951__ $$a2026-01-15-12:36:34
000165847 980__ $$aARTICLE