165908 20260116002211.0 doi 10.1093/ve/veab038 sideral 143301 ART-2021-143301 eng Dudas, Gytis Polymorphism of genetic ambigrams 2021 Double synonyms in the genetic code can be used as a tool to test competing hypotheses regarding ambigrammatic narnavirus genomes. Applying the analysis to recent observations of Culex narnavirus 1 and Zhejiang mosquito virus 3 ambigrammatic viruses indicates that the open reading frame on the complementary strand of the segment coding for RNA-dependent RNA polymerase does not code for a functional protein. Culex narnavirus 1 has been shown to possess a second segment, also ambigrammatic, termed ‘Robin’. We find a comparable segment for Zhejiang mosquito virus 3, a moderately diverged relative of Culex narnavirus 1. Our analysis of Robin polymorphisms suggests that its reverse open reading frame also does not code for a functional protein. We make a hypothesis about its role. Access copy available to the general public Unrestricted info:eu-repo/semantics/openAccess by https://creativecommons.org/licenses/by/4.0/deed.es 5.614 2021 VIROLOGY 15 / 37 = 0.405 2021 Q2 T2 2.256 2021 Virology 2021 Q1 Microbiology 2021 Q1 6.1 2021 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Huber, Greg Wilkinson, Michael Yllanes, David (orcid)0000-0001-7276-2942 7, 1 (2021), veab038 [11 pp.] Virus evolution 2057-1577 609002 http://zaguan.unizar.es/record/165908/files/texto_completo.pdf Versión publicada 2542161 http://zaguan.unizar.es/record/165908/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:165908 articulos driver 2026-01-15-21:56:21 ARTICLE