000166047 001__ 166047
000166047 005__ 20260119170325.0
000166047 0247_ $$2doi$$a10.1016/j.chemosphere.2022.135473
000166047 0248_ $$2sideral$$a129810
000166047 037__ $$aART-2022-129810
000166047 041__ $$aeng
000166047 100__ $$aPino-Otín, María Rosa
000166047 245__ $$aImpact of eight widely consumed antibiotics on the growth and physiological profile of natural soil microbial communities
000166047 260__ $$c2022
000166047 5060_ $$aAccess copy available to the general public$$fUnrestricted
000166047 5203_ $$aAntibiotics’ (ATBs) occurrence in soil ecosystems has a relevant effect in the structure and functionality of edaphic microbial communities, mainly because of their amendment with manure and biosolids that alter their key ecological functions.
In this study, the impact of eight widely consumed ATBs on a natural soil microbial community, characterized through 16 S rRNA gene sequencing, was evaluated. Changes induced by the ATBs in the growth of the soil microbiota and in the community-level physiological profiling (CLPP), using Biolog EcoPlates™, were measured as endpoint.
The eight assayed ATBs lead to a significant decrease in the growth of soil microbial communities in a dose-dependent way, ordered by its effect as follows: chloramphenicol > gentamycin > erythromycin > ampicillin > penicillin > amoxicillin > tetracycline > streptomycin. Chloramphenicol, gentamycin, and erythromycin adversely affected the physiological profile of the soil community, especially its ability to metabolize amino acids, carboxylic and ketonic acids and polymers. The analysis of the relationship between the physico-chemical properties of ATBs, as well as their mechanism of action, revealed that, except for the aminoglycosides, each ATB is influenced by a different physico-chemical parameters, even for ATBs of the same family.
Significant effects were detected from 100 μg mL to 1, concentrations that can be found in digested sludge, biosolids and even in fertilized soils after repeated application of manure, so cumulative and long-term effects of these antibiotics on soil environment cannot be ruled out.
000166047 536__ $$9info:eu-repo/grantAgreement/ES/DGA/E39-20R
000166047 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
000166047 590__ $$a8.8$$b2022
000166047 591__ $$aENVIRONMENTAL SCIENCES$$b30 / 275 = 0.109$$c2022$$dQ1$$eT1
000166047 592__ $$a1.727$$b2022
000166047 593__ $$aChemistry (miscellaneous)$$c2022$$dQ1
000166047 593__ $$aEnvironmental Chemistry$$c2022$$dQ1
000166047 593__ $$aEnvironmental Engineering$$c2022$$dQ1
000166047 593__ $$aPublic Health, Environmental and Occupational Health$$c2022$$dQ1
000166047 593__ $$aMedicine (miscellaneous)$$c2022$$dQ1
000166047 593__ $$aPollution$$c2022$$dQ1
000166047 593__ $$aHealth, Toxicology and Mutagenesis$$c2022$$dQ1
000166047 594__ $$a13.3$$b2022
000166047 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000166047 700__ $$aFerrando, Natalia
000166047 700__ $$aBallestero, Diego
000166047 700__ $$aLanga, Elisa
000166047 700__ $$aRoig, Francisco J.
000166047 700__ $$0(orcid)0000-0001-8511-5218$$aTerrado, Eva M.$$uUniversidad de Zaragoza
000166047 7102_ $$14013$$2205$$aUniversidad de Zaragoza$$bDpto. Didácticas Específicas$$cÁrea Didáctica Ciencias Exper.
000166047 773__ $$g305 (2022), 135473 [12 pp]$$pChemosphere$$tCHEMOSPHERE$$x0045-6535
000166047 8564_ $$s2681645$$uhttps://zaguan.unizar.es/record/166047/files/texto_completo.pdf$$yPostprint
000166047 8564_ $$s1883341$$uhttps://zaguan.unizar.es/record/166047/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000166047 909CO $$ooai:zaguan.unizar.es:166047$$particulos$$pdriver
000166047 951__ $$a2026-01-19-14:38:54
000166047 980__ $$aARTICLE