000166125 001__ 166125
000166125 005__ 20260120151004.0
000166125 0247_ $$2doi$$a10.3390/reactions6040059
000166125 0248_ $$2sideral$$a147525
000166125 037__ $$aART-2025-147525
000166125 041__ $$aeng
000166125 100__ $$aMansilla, Daniela S.
000166125 245__ $$aBis- and Azabis(oxazoline)–Copper–Tungstophosphate Immobilized on mesoporous silica: preparation and use as catalyst in enantioselective cyclopropanation
000166125 260__ $$c2025
000166125 5060_ $$aAccess copy available to the general public$$fUnrestricted
000166125 5203_ $$aTungstophosphoric acid (TPA) has been supported on mesoporous silicas prepared using urea as the pore forming agent. The amount of urea (20, 30, or 40% w/w) influences the silica specific surface area (SBET), total pore volume (Vp), and average pore diameter (Dp). The materials synthetized using 20% w/w (SiU20) display mainly mesoporous structures, with the highest Vp and Dp values being chosen to be used as TPA support. The SiU20-TPA solids with different TPA loadings (10, 20, or 30% w/w) have been used as supports for chiral copper catalysts with bis(oxazoline) or azabis(oxazoline) ligands. The catalytic efficiency of enantioselective cyclopropanation strongly depends on support morphology and TPA loading. SiU-TPA20 has been shown to be the optimal one. The stability of the complex is also a very important parameter, and the best results are obtained with an excess of chiral ligand to ensure the correct formation of the complex on the solid. In this way, with azabox-Cu/SiU20-TPA20 it is possible to obtain a highly selective (90% ee for the trans-cyclopropanes) and recoverable catalyst.
000166125 536__ $$9info:eu-repo/grantAgreement/ES/DGA/E07-23R$$9info:eu-repo/grantAgreement/ES/MICINN/PID2021-125762NB-I00
000166125 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000166125 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000166125 700__ $$aPizzio, Luis R.
000166125 700__ $$0(orcid)0000-0003-1570-4257$$aMayoral, José A.$$uUniversidad de Zaragoza
000166125 700__ $$0(orcid)0000-0002-0136-5138$$aFraile, José M.
000166125 700__ $$aTorviso, M. Rosario
000166125 7102_ $$12013$$2765$$aUniversidad de Zaragoza$$bDpto. Química Orgánica$$cÁrea Química Orgánica
000166125 773__ $$g6, 4 (2025), 59 [13 pp.]$$tReactions (Basel)$$x2624-781X
000166125 8564_ $$s3702334$$uhttps://zaguan.unizar.es/record/166125/files/texto_completo.pdf$$yVersión publicada
000166125 8564_ $$s2610013$$uhttps://zaguan.unizar.es/record/166125/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000166125 909CO $$ooai:zaguan.unizar.es:166125$$particulos$$pdriver
000166125 951__ $$a2026-01-20-14:18:10
000166125 980__ $$aARTICLE