Abstract: The present study of the Cueva de Luzán (Los Fayos Zaragoza), located in the geological context of the Ebro Basin and the Iberian Cordillera, aims to carry out a geomorphological and geological characterisation of the cave, as well as to investigate its possible genesis and evolution. The cave is located in the limestones of the Oncala Group (Upper Cretaceous) and forms part of the karstic system that supplies the Ojo de San Juan spring in Tarazona. The research includes methods such as mapping, stratigraphic and hydrogeological analysis, characterisation of the internal morphologies and deposits and the application of techniques such as 3D topography. This work provides evidence of the speleogenesis of the Cueva de Luzán, through the study of internal morphologies and cave deposits. From this analysis, two stages of evolution have been established for the formation and evolution of the cave. The boxwork structures, the tubes with ascending domes and the differential dissolution morphologies such as the ‘Stone Bridge’ suggest that the cave was formed under phreatic conditions. Subsequently, the cavity underwent a transition to vadose conditions as a result of a lowering of the base level of the aquifer. It is at this time that the epigenic morphologies were generated, such as the grooves found in the ‘Horizontal Tube’ and the internal gravitational and alluvial deposits. The clastic deposits found at the entrance to the cave provide information about the opening of the cavity to the exterior and about the alluvial processes that almost completely clogged the entrance at some point in its evolution. The transition from phreatic to vadose conditions could be related to the opening of the Ebro Basin, an event that caused a transition to exorheic conditions and initiated an incision of the drainage network due to a lowering of the general base level of the basin. The final aim of this work is to offer a hypothesis that explains the origin and evolution of the cavity,