000168114 001__ 168114
000168114 005__ 20260126155510.0
000168114 0247_ $$2doi$$a10.1093/ejcts/ezac170
000168114 0248_ $$2sideral$$a147673
000168114 037__ $$aART-2022-147673
000168114 041__ $$aeng
000168114 100__ $$aGómez de Antonio, David
000168114 245__ $$aExternal validation of the European Society of Thoracic Surgeons morbidity and mortality risk models
000168114 260__ $$c2022
000168114 5203_ $$aOBJECTIVES
There is a wide variety of predictive models of postoperative risk, although some of them are specific to thoracic surgery, none of them is widely used. The European Society for Thoracic Surgery has recently updated its models of cardiopulmonary morbidity (Eurolung 1) and 30-day mortality (Eurolung 2) after anatomic lung resection. The aim of our work is to carry out the external validation of both models in a multicentre national database.
METHODS
External validation of Eurolung 1 and Eurolung 2 was evaluated through calibration (calibration plot, Brier score and Hosmer–Lemeshow test) and discrimination [area under receiver operating characteristic curves (AUC ROC)], on a national multicentre database of 2858 patients undergoing anatomic lung resection between 2016 and 2018.
RESULTS
For Eurolung 1, calibration plot showed suboptimal overlapping (slope = 0.921) and a Hosmer–Lemeshow test and Brier score of P = 0.353 and 0.104, respectively. In terms of discrimination, AUC ROC for Eurolung 1 was 0.653 (95% confidence interval, 0.623–0.684). In contrast, Eurolung 2 showed a good calibration (slope = 1.038) and a Hosmer–Lemeshow test and Brier score of P = 0.234 and 0.020, respectively. AUC ROC for Eurolung 2 was 0.760 (95% confidence interval, 0.701–0.819).
CONCLUSIONS
Thirty-day mortality score (Eurolung 2) seems to be transportable to other anatomic lung-resected patients. On the other hand, postoperative cardiopulmonary morbidity score (Eurolung 1) seems not to have sufficient generalizability for new patients.
000168114 540__ $$9info:eu-repo/semantics/closedAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000168114 590__ $$a3.4$$b2022
000168114 591__ $$aSURGERY$$b39 / 213 = 0.183$$c2022$$dQ1$$eT1
000168114 591__ $$aCARDIAC & CARDIOVASCULAR SYSTEMS$$b63 / 143 = 0.441$$c2022$$dQ2$$eT2
000168114 591__ $$aRESPIRATORY SYSTEM$$b33 / 66 = 0.5$$c2022$$dQ2$$eT2
000168114 592__ $$a1.183$$b2022
000168114 593__ $$aCardiology and Cardiovascular Medicine$$c2022$$dQ1
000168114 593__ $$aSurgery$$c2022$$dQ1
000168114 593__ $$aPulmonary and Respiratory Medicine$$c2022$$dQ1
000168114 593__ $$aMedicine (miscellaneous)$$c2022$$dQ1
000168114 594__ $$a5.7$$b2022
000168114 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000168114 700__ $$aCrowley Carrasco, Silvana
000168114 700__ $$aRomero Román, Alejandra
000168114 700__ $$aRoyuela, Ana
000168114 700__ $$aGil Barturen, Mariana
000168114 700__ $$aObiols, Carme
000168114 700__ $$aCall, Sergi
000168114 700__ $$aRoyo, Ínigo
000168114 700__ $$aRecuero, José Luis
000168114 700__ $$aCabanero, Alberto
000168114 700__ $$aMoreno, Nicolás
000168114 700__ $$0(orcid)0000-0003-0249-3104$$aEmbún, Raúl$$uUniversidad de Zaragoza
000168114 7102_ $$11013$$2090$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Cirugía
000168114 773__ $$g62, 3 (2022), [8 pp.]$$pEur. j. cardio-thorac. surg.$$tEUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY$$x1010-7940
000168114 8564_ $$s841847$$uhttps://zaguan.unizar.es/record/168114/files/texto_completo.pdf$$yVersión publicada
000168114 8564_ $$s1628075$$uhttps://zaguan.unizar.es/record/168114/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000168114 909CO $$ooai:zaguan.unizar.es:168114$$particulos$$pdriver
000168114 951__ $$a2026-01-26-14:50:49
000168114 980__ $$aARTICLE