000168292 001__ 168292 000168292 005__ 20260202151222.0 000168292 0247_ $$2doi$$a10.1016/j.jtemb.2025.127810 000168292 0248_ $$2sideral$$a147784 000168292 037__ $$aART-2025-147784 000168292 041__ $$aeng 000168292 100__ $$aCrépeaux, Guillemette 000168292 245__ $$aAluminium adjuvants and childhood health: a call for science 000168292 260__ $$c2025 000168292 5203_ $$aIn July 2025, Andersson et al. reported in Annals of Internal Medicine that early-life exposure to Aluminium (Al)-adjuvanted vaccines was not associated with increased risk of 50 chronic diseases, based on a Danish cohort of 1.2 million children. While widely cited as reassuring evidence of Al-Based Adjuvant (ABA) safety, closer scrutiny reveals major methodological and conceptual flaws. Specifically, the study demonstrates limited understanding of Al toxicology, weaknesses in cohort design and statistical analysis, and insufficient transparency regarding potential conflicts of interest. We argue that these shortcomings prevent meaningful conclusions about ABA safety, particularly in relation to neurodevelopmental and autoimmune outcomes, and highlight the need for more rigorous, transparent, and scientifically grounded investigations. 000168292 540__ $$9info:eu-repo/semantics/closedAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/ 000168292 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000168292 700__ $$aHammond, Jeremy R. 000168292 700__ $$aHandley, Jonathan B. 000168292 700__ $$aHooker, Brian 000168292 700__ $$aJablonowski, Karl 000168292 700__ $$0(orcid)0000-0002-2053-9842$$aLuján, Lluís$$uUniversidad de Zaragoza 000168292 700__ $$aLyons-Weiler, James 000168292 700__ $$aNosten-Bertrand, Marika 000168292 700__ $$aShaw, Christopher A. 000168292 700__ $$aShoenfeld, Yehuda 000168292 700__ $$aTomljenovic, Lucija 000168292 700__ $$aExley, Christopher 000168292 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Sanidad Animal 000168292 773__ $$g93 (2025), 127810 [6 pp.]$$pJ. trace elem. med. biol.$$tJOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY$$x0946-672X 000168292 8564_ $$s550993$$uhttps://zaguan.unizar.es/record/168292/files/texto_completo.pdf$$yVersión publicada 000168292 8564_ $$s2392882$$uhttps://zaguan.unizar.es/record/168292/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000168292 909CO $$ooai:zaguan.unizar.es:168292$$particulos$$pdriver 000168292 951__ $$a2026-02-02-14:40:07 000168292 980__ $$aARTICLE