000168294 001__ 168294
000168294 005__ 20260202151222.0
000168294 0247_ $$2doi$$a10.1080/1828051X.2025.2596280
000168294 0248_ $$2sideral$$a147785
000168294 037__ $$aART-2025-147785
000168294 041__ $$aeng
000168294 100__ $$aHassan, Mahmoud
000168294 245__ $$aEffects of dietary supplementation of pre-weaned lambs with live yeast on rumen fermentation, gut development, performance, and blood health indicators
000168294 260__ $$c2025
000168294 5060_ $$aAccess copy available to the general public$$fUnrestricted
000168294 5203_ $$aThis study evaluated the effects of supplementing pre-weaned lambs with live yeast (Saccharomyces cerevisiae CNCM I-1077; 3 x 10<^>9 CFU/kg DM) on rumen fermentation, blood metabolites, gut development, and performance. Forty-six male lambs were randomly assigned to two treatments in a completely randomised design: a control group (CTL) fed a starter concentrate, and a yeast group (YST) receiving the same concentrate supplemented with live yeast. Both groups had ad libitum access to diets and barley straw from two weeks of age until weaning at eight weeks. Rumen fluid and blood samples were collected at 7 and 10 weeks to assess fermentation parameters and metabolites, and rumen tissue samples were collected at slaughter to evaluate papillae development. Rumen fermentative activity increased from 7 to 10 weeks, with higher concentrations of volatile fatty acids (VFA), lactate, and ammonia-N (p<0.001). YST lambs showed higher rumen concentrations of protozoa (p-0.007) and anaerobic fungi (p-0.009), and a 56% increase in total VFA concentration pre-weaning and slightly enhanced concentrate intake. Blood metabolites remained within a physiological range, and YST lambs showed higher b-hydroxybutyrate (p<0.001) and total protein (p-0.054) than CTL lambs. Yeast also reduced parakeratosis scores (p<0.001) and increased papillae width (p-0.020). However, growth performance was not significantly affected. These results suggest that live yeast supplementation during the pre-weaning period supports microbial colonisation and rumen papillae development, facilitating a smoother transition from liquid to solid feeding and improved rumen function post-weaning.
000168294 536__ $$9info:eu-repo/grantAgreement/EC/H2020/ 818368/EU/Microbiome Applications for Sustainable food systems through Technologies and EnteRprise/MASTER$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 818368-MASTER$$9info:eu-repo/grantAgreement/ES/MICINN/RYC2019-027764-I/AEI/10.13039/501100011033
000168294 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000168294 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000168294 700__ $$0(orcid)0000-0001-5880-6021$$aBelanche, Alejandro$$uUniversidad de Zaragoza
000168294 700__ $$aRomera-Recio, Eva
000168294 700__ $$aRodríguez, Bernardo
000168294 700__ $$aRivelli, Ines
000168294 700__ $$aGauthier, Marine
000168294 700__ $$aYáñez-Ruiz, David R.
000168294 7102_ $$12008$$2700$$aUniversidad de Zaragoza$$bDpto. Produc.Animal Cienc.Ali.$$cÁrea Producción Animal
000168294 773__ $$g24, 1 (2025), 2653-2669$$pItal. J. Anim. Sci.$$tItalian Journal of Animal Science$$x1594-4077
000168294 8564_ $$s2120209$$uhttps://zaguan.unizar.es/record/168294/files/texto_completo.pdf$$yVersión publicada
000168294 8564_ $$s1207254$$uhttps://zaguan.unizar.es/record/168294/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000168294 909CO $$ooai:zaguan.unizar.es:168294$$particulos$$pdriver
000168294 951__ $$a2026-02-02-14:40:09
000168294 980__ $$aARTICLE