000168326 001__ 168326
000168326 005__ 20260204153543.0
000168326 0247_ $$2doi$$a10.1093/europace/euz330
000168326 0248_ $$2sideral$$a146845
000168326 037__ $$aART-2020-146845
000168326 041__ $$aeng
000168326 100__ $$aPenela, D
000168326 245__ $$aInfluence of baseline QRS on the left ventricular ejection fraction recovery after frequent premature ventricular complex ablation.
000168326 260__ $$c2020
000168326 5203_ $$aAims
Frequent premature ventricular complexes (PVCs) can induce or worsen left ventricular systolic dysfunction. We aimed to investigate the influence of the baseline QRS in the response after PVC ablation in patients with depressed left ventricular ejection fraction (LVEF).
Methods and results
Two hundred and fifteen [59 ± 13 years old, 152 (71%) men] consecutive patients with left ventricular (LV) systolic dysfunction and frequent PVCs referred for ablation were included and followed-up for 12 months. Echocardiographic response was defined as an improvement of at least five absolute points in LVEF. Clinical, electrocardiogram, and electrophysiological characteristics were analysed. Mean baseline QRS duration was 110 ms [97–140]. Premature ventricular complex burden significantly decreased after ablation from 23% [16–33] at baseline to 1% [0–8] at 12 months, P < 0.001. Mean PVC burden reduction was 18 [8–30] points. There was a significant improvement of LVEF from 35% [29–40] at baseline to 44% [35–55] at 12 months, P < 0.001. One hundred and thirty (61%) patients were considered as echocardiographic responders. Baseline QRS duration (ms) [odds ratio (OR) 0.98 (0.97–0.99), P = 0.01] was an independent predictor of echocardiographic response. Mean LVEF improvement was 16 [10–21] points when the baseline QRS duration was <90 ms; 12 [4–20] when it was 90–110 ms; 5 [0–15] when it was 110 ± 130 ms; and 0 [0–6] points when it was >130 ms.
Conclusions
In patients with LV systolic dysfunction, intrinsic QRS duration is inversely related to the probability and the degree of echocardiographic response after frequent PVC ablation. Patients with a QRS duration >130 ms at baseline have the poorer response after ablation.
000168326 540__ $$9info:eu-repo/semantics/closedAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000168326 590__ $$a5.214$$b2020
000168326 591__ $$aCARDIAC & CARDIOVASCULAR SYSTEMS$$b40 / 141 = 0.284$$c2020$$dQ2$$eT1
000168326 592__ $$a2.119$$b2020
000168326 593__ $$aPhysiology (medical)$$c2020$$dQ1
000168326 593__ $$aCardiology and Cardiovascular Medicine$$c2020$$dQ1
000168326 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000168326 700__ $$0(orcid)0000-0001-9187-1773$$aJáuregui, B
000168326 700__ $$aFernández-Armenta, J
000168326 700__ $$aAguinaga, L
000168326 700__ $$aTercedor, L
000168326 700__ $$aOrdóñez, A
000168326 700__ $$aAcosta, J
000168326 700__ $$aBisbal, F
000168326 700__ $$aVassanelli, F
000168326 700__ $$aTeres, C
000168326 700__ $$aAceña, M
000168326 700__ $$aMartí-Almor, J
000168326 700__ $$aDe Sensi, F
000168326 700__ $$aVatasescu, R
000168326 700__ $$aBorràs, R
000168326 700__ $$aSánchez Millán, P
000168326 700__ $$aSoto-Iglesias, D
000168326 700__ $$aOller Martínez, G
000168326 700__ $$aCarballo, J
000168326 700__ $$aBerruezo, A
000168326 773__ $$g22 (2020), 274 - 280$$pEuropace$$tEuropace$$x1099-5129
000168326 8564_ $$s311420$$uhttps://zaguan.unizar.es/record/168326/files/texto_completo.pdf$$yVersión publicada
000168326 8564_ $$s2452451$$uhttps://zaguan.unizar.es/record/168326/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000168326 909CO $$ooai:zaguan.unizar.es:168326$$particulos$$pdriver
000168326 951__ $$a2026-02-04-13:13:49
000168326 980__ $$aARTICLE