000169125 001__ 169125
000169125 005__ 20260219161517.0
000169125 0247_ $$2doi$$a10.1016/j.seppur.2026.136740
000169125 0248_ $$2sideral$$a147918
000169125 037__ $$aART-2026-147918
000169125 041__ $$aeng
000169125 100__ $$aMoore, Benjamin Stewart
000169125 245__ $$aPursuing antifouling performance: Hydrophilic PES-Siloxene membranes for enhanced biological applications
000169125 260__ $$c2026
000169125 5060_ $$aAccess copy available to the general public$$fUnrestricted
000169125 5203_ $$aMembranes are widely used in biomedical applications due to their efficient separations necessary for a variety of applications, ranging from pre-treatments to hemofiltration. These membranes often suffer fouling from high-concentration biological components, such as blood plasma proteins, which limits the separation performance. However, at research level, they are commonly tested using much lower feed concentrations that are not representative of real conditions. Developing and testing a membrane under high feed concentrations, analogous to those used during practical applications, its fouling resistance can be more realistically assessed. In this work, siloxene, an easy-to-synthesise hydrophilic, two-dimensional nanomaterial, was successfully incorporated as a filler into the polyethersulfone (PES) membrane matrix. At optimised filler loadings of 0.15 wt%, porosity rose to 83 %, zeta potential was enhanced to −35.4 mV and high hydrophilicity was achieved with a water contact angle as low as 27°. Pure water permeance increased from 75 to 147 LMHBar, compared to PES, while rejecting ∼99 % bovine serum albumin (BSA). Furthermore, the flux recovery ratio increased from 17 % to 62 %, therefore improving the use of effective membrane area. PES-siloxene membranes showed significant improvement in their capability to cope with concentrated biological feeds analogous to human blood plasma protein concentration: 80 g L−1 BSA solution. PES-Siloxene membranes also superseded the performance of commercial PES “protein-resistant” membrane and functionalised-graphene oxide in an equivalent matrix, highlighted in the literature for its protein antifouling properties. Overall, PES-siloxene MMM results in a low-cost, protein-resistant, and biocompatible membrane that maintains high selectivity suitable for biomedical applications.
000169125 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000169125 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000169125 700__ $$aLópez-Porfiri, Pablo
000169125 700__ $$aMahalingam, Dinesh K.
000169125 700__ $$aCraddock, Elliot
000169125 700__ $$aAlbiladi, Abdullah
000169125 700__ $$aD'Agostino, Carmine
000169125 700__ $$aChew, John
000169125 700__ $$aMattia, Davide
000169125 700__ $$0(orcid)0000-0002-6905-714X$$aGorgojo, Patricia$$uUniversidad de Zaragoza
000169125 700__ $$aPérez-Page, María
000169125 7102_ $$15005$$2555$$aUniversidad de Zaragoza$$bDpto. Ing.Quím.Tecnol.Med.Amb.$$cÁrea Ingeniería Química
000169125 773__ $$g388 (2026), 136740 [15 pp.]$$pSep. Purif. Technol.$$tSeparation and Purification Technology$$x1383-5866
000169125 8564_ $$s6744261$$uhttps://zaguan.unizar.es/record/169125/files/texto_completo.pdf$$yVersión publicada
000169125 8564_ $$s2427478$$uhttps://zaguan.unizar.es/record/169125/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000169125 909CO $$ooai:zaguan.unizar.es:169125$$particulos$$pdriver
000169125 951__ $$a2026-02-19-14:11:02
000169125 980__ $$aARTICLE