169146 20260220162133.0 doi 10.1016/j.acuro.2025.501919 sideral 148231 ART-2025-148231 spa Gómez Rivas, J. El futuro del cribado del cáncer de próstata en la Unión Europea: programa PRAISE-U 2025 ntroduction: Prostate cancer (PCa) remains one of the leading public health challenges among European men. Despite technological advances, its early detection continues to be controversial due to the risk of overdiagnosis and the limited adoption of organized screening programs. Materials and methods: A review was conducted of scientific literature, institutional reports, and technical documentation from the PRAISE-U project. We describe the key components of its design, implementation and lessons learned at two pilot sites in Spain (Galicia and Manresa), with a focus on personalized strategies and operational efficiency. Results: Based on the European Union recommendation of 2022, the PRAISE-U project promotes a risk-based screening program that incorporates prostate-specific antigen (PSA), magnetic resonance imaging (MRI) and risk calculators (RC). Galicia and Manresa have developed screening circuits adapted to their health systems. Galicia has managed to invite 7,000 of the 12,000 target men in less than a year, integrating digital tools and direct contact strategies. Manresa, from primary care, has developed a coordinated approach focused on accessibility and traceability. Both models prioritize equity, adherence and minimization of overtreatment. Conclusions: The PRAISE-U project offers an innovative and adaptable framework for PCa screening in Europe. The Spanish experience demonstrates that it is possible to implement effective and risk-focused early detection programs, provided that there is sound planning, technological tools and a collaborative approach between levels of care. info:eu-repo/grantAgreement/EU4HEALTH 101101217 info:eu-repo/semantics/closedAccess All rights reserved http://www.europeana.eu/rights/rr-f/ info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Gómez Dávila, P. Tarrazo Antelo, A.M. Corujo Quinteiro, M. Gómez Amorín, Á. Rodríguez Alonso, A. Vilaseca, J.M. López, H. Salazar, J.P. Borque-Fernando, Á. Universidad de Zaragoza (orcid)0000-0003-0178-4567 Moreno-Sierra, J. Collen, S. Beyer, K. Helleman, J. Roobol, M.J. van Poppel, H. 1013 817 Universidad de Zaragoza Dpto. Cirugía Área Urología (2025), 501919 [6 pp.] Actas urol. esp. Actas urológicas españolas 0210-4806 1052018 http://zaguan.unizar.es/record/169146/files/texto_completo.pdf Versión publicada 2285917 http://zaguan.unizar.es/record/169146/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:169146 articulos driver 2026-02-20-14:53:51 ARTICLE