169334 20260225105428.0 doi 10.1097/PAS.0000000000001186 sideral 110918 ART-2019-110918 eng Prieto-Torres, L. The spectrum of EBV-positive mucocutaneous ulcer 2019 We describe a series of 9 patients with Epstein-Barr virus (EBV)-positive mucocutaneous lymphoproliferative lesions that broadens the concept of EBV-positive mucocutaneous ulcer. We report 5 female and 4 male patients, with an average age of 74 years (range, 55 to 87 y), 2 of whom were HIV-positive. The lesions were located in the oropharynx, skin, and rectal and/or genital mucosa. Histopathologically, 6 cases showed a polymorphic pattern and 3 had a monomorphic and diffuse one, with angiotropism in 4 cases (2 each with the polymorphic and monomorphic patterns). Three of the cases expressed PDL1. In addition to its presence in the neoplastic lymphoid cells, EBV was also detected in adjacent epithelial cells in an oropharyngeal lesion. All cases responded to local therapy or adapted systemic chemotherapy in selected cases. This series extends the spectrum of this disorder to include some HIV-positive cases, patients with multiple lesions confined to a single anatomic area, lesions with an angiocentric pattern, and some cases with monomorphous large-cell cytology. We discuss the differential clinicopathologic diagnosis of this disorder and that of classic EBV large B-cell lymphoma. Copyright info:eu-repo/semantics/closedAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 4.958 2019 SURGERY 10 / 209 = 0.048 2019 Q1 T1 PATHOLOGY 10 / 78 = 0.128 2019 Q1 T1 2.734 2019 Anatomy 2019 Q1 Surgery 2019 Q1 Pathology and Forensic Medicine 2019 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Eraña, I. Gil-Redondo, R. Gómez De La Riva, I. Manso, R. Pajares, R. Córdoba, R. Machan, S. Ara, M. Universidad de Zaragoza (orcid)0000-0001-8789-6783 Requena, L. Piris, M.Á. Rodríguez-Pinilla, S.M. 1007 183 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Área Dermatología 43, 2 (2019), 201-210 Am. j. surg. pathol. AMERICAN JOURNAL OF SURGICAL PATHOLOGY 0147-5185 649814 http://zaguan.unizar.es/record/169334/files/texto_completo.pdf Versión publicada 3241574 http://zaguan.unizar.es/record/169334/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:169334 articulos driver 2026-02-24-14:46:55 ARTICLE