169336 20260225105429.0 doi 10.1097/PAS.0000000000001287 sideral 114268 ART-2019-114268 eng Prieto-Torres, L. Large Cells With CD30 Expression and Hodgkin-like Features in Primary Cutaneous Marginal Zone B-Cell Lymphoma A Study of 13 Cases 2019 The presence of CD30(+) cells in cutaneous lymphomas has come to prominence in recent years as a potential diagnostic and therapeutic marker. In primary cutaneous marginal zone B-cell lymphomas, the presence of large CD30(+) cells with Hodgkin-like features and their significance have not yet been studied. Here we describe the main clinical, histologic, immunophenotypic, and molecular characteristics of 13 cases of primary cutaneous marginal zone lymphomas featuring >10% of CD30(+) large cells, and analyze their relationship with histologic and clinical progression of the disease and with other morphologic and immunophenotypic features. We report 10 male and 3 female patients, 4 with early-local disease and 8 with locoregional advanced disease without extracutaneous involvement but with a high relapse rate of 69%. We describe an association between a high level of CD30 expression and disease progression, with increased clinical recurrence in cases with >15% of CD30(+) cells. We also discuss the differential diagnosis with other cutaneous and systemic lymphomas, especially Hodgkin lymphoma. info:eu-repo/semantics/closedAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 4.958 2019 SURGERY 10 / 209 = 0.048 2019 Q1 T1 PATHOLOGY 10 / 78 = 0.128 2019 Q1 T1 2.734 2019 Anatomy 2019 Q1 Surgery 2019 Q1 Pathology and Forensic Medicine 2019 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Manso, R. Cieza-Diaz, D.E. Jo, M Perez, L.K. Montenegro-Damaso, T. Eraña, I. Lorda, M. Massa, D.S. Machan, S. Cordoba, R. Ara, M. Universidad de Zaragoza (orcid)0000-0001-8789-6783 Requena, L. Rodriguez-Pinilla, S.M. Piris, M.A. 1007 183 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Área Dermatología 43, 9 (2019), 1191-1202 Am. j. surg. pathol. AMERICAN JOURNAL OF SURGICAL PATHOLOGY 0147-5185 781082 http://zaguan.unizar.es/record/169336/files/texto_completo.pdf Versión publicada 3114294 http://zaguan.unizar.es/record/169336/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:169336 articulos driver 2026-02-24-14:46:59 ARTICLE