000169382 001__ 169382
000169382 005__ 20260225105429.0
000169382 0247_ $$2doi$$a10.1093/pm/pnaf170
000169382 0248_ $$2sideral$$a148310
000169382 037__ $$aART-2025-148310
000169382 041__ $$aeng
000169382 100__ $$aBorrella-Andrés, Sergio
000169382 245__ $$aEffect of ultrasound-guided percutaneous electrolysis and nerve stimulation on pain and function in carpal tunnel syndrome: A randomized clinical trial
000169382 260__ $$c2025
000169382 5060_ $$aAccess copy available to the general public$$fUnrestricted
000169382 5203_ $$aObjective
To assess the effectiveness of ultrasound-guided percutaneous electrolysis and peripheral nerve stimulation in reducing pain, improving functional capacity, and modifying mechanosensitivity responses in patients with carpal tunnel syndrome compared to a sham intervention.
Design
A multicenter, randomized controlled clinical trial.
Settings
Double center pain clinic.
Subjects
In brief, 46 patients diagnosed, with carpal tunnel syndrome, assigned to an intervention group or a sham group.
Methods
Both groups received 3 sessions over 4 weeks. Primary outcomes included mean and worst pain intensity. Secondary outcomes assessed functional status and symptoms severity; Boston Carpal Tunnel Questionnaire, Upper Limb Neurodynamic Test 1, grip and pinch strength, two-point discrimination, sensory thresholds, pressure pain threshold and Global Rating of Change Scale. Follow-ups were conducted at 4, 12, and 24 weeks.
Results
Statistically significant intergroup differences were observed for all evaluated variables across follow-ups, except for grip and pinch strength. The intervention group demonstrated significantly greater improvements in pain intensity, functional disability, sensory thresholds, and neural mobility, with large effect sizes ranging from 0.64 to 2.09. Notably, the improvements in pain and function were sustained at 6 months.
Conclusions
Ultrasound-guided percutaneous electrolysis and peripheral nerve stimulation significantly reduce pain and improve function in carpal tunnel syndrome, offering a promising minimally invasive alternative to standard care.
000169382 540__ $$9info:eu-repo/semantics/embargoedAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000169382 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000169382 700__ $$aRodríguez-Sanz, Jacobo
000169382 700__ $$aLópez-de-Celis, Carlos
000169382 700__ $$aMarqués García, Isabel
000169382 700__ $$0(orcid)0000-0002-0026-9224$$aBueno-Gracia, Elena$$uUniversidad de Zaragoza
000169382 700__ $$aRodríguez-Mena, Diego$$uUniversidad de Zaragoza
000169382 700__ $$0(orcid)0000-0001-9080-0543$$aMalo-Urriés, Miguel$$uUniversidad de Zaragoza
000169382 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000169382 7102_ $$11006$$2413$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Fisioterapia
000169382 773__ $$g(2025), [15 pp.]$$pPain med.$$tPain Medicine (United States)$$x1526-2375
000169382 8564_ $$s482829$$uhttps://zaguan.unizar.es/record/169382/files/texto_completo.pdf$$yPostprint$$zinfo:eu-repo/date/embargoEnd/2028-01-13
000169382 8564_ $$s1562707$$uhttps://zaguan.unizar.es/record/169382/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint$$zinfo:eu-repo/date/embargoEnd/2028-01-13
000169382 909CO $$ooai:zaguan.unizar.es:169382$$particulos$$pdriver
000169382 951__ $$a2026-02-24-14:47:56
000169382 980__ $$aARTICLE