000169935 001__ 169935 000169935 005__ 20260306154908.0 000169935 0247_ $$2doi$$a10.1016/j.tvjl.2026.106619 000169935 0248_ $$2sideral$$a148438 000169935 037__ $$aART-2026-148438 000169935 041__ $$aeng 000169935 100__ $$0(orcid)0000-0001-7575-6599$$aEsteban Jiménez, Juan José$$uUniversidad de Zaragoza 000169935 245__ $$aFeline panleukopenia: Analysis of possible survival biomarkers 000169935 260__ $$c2026 000169935 5060_ $$aAccess copy available to the general public$$fUnrestricted 000169935 5203_ $$aFeline panleukopenia virus (FPV), also known as feline parvovirus, is a very common viral disease in cats, characterized by its high case fatality rate, for which the establishment of clear prognostic thresholds is complicated. The aim of this study was to evaluate the clinical relevance of different demographical, hematological, and biochemical variables and indexes obtained at hospital admission as potential prognostic factors for survival. A study was carried out of 58 cats diagnosed with FPV between 2017 and 2025 at the Veterinary Teaching Hospital of the University of Zaragoza. Variables analyzed included age, sex, hematocrit, counts of leukocytes, neutrophils, lymphocytes and platelets, neutrophil:lymphocyte ratio (NLR), platelet:lymphocyte ratio (PLR), albumin and potassium. The observed case fatality rate was 10.3% (6/58). No significant differences in survival were identified relative to age, sex, or the hematologic/biochemical indexes analyzed, although non-survivors tended to show lower hematocrit, albumin and neutrophil values together with relative lymphocytosis. These findings suggest that hematologic indexes such as NLR and PLR have limited utility in the feline species. Future studies with larger sample sizes and dynamic monitoring of biomarkers during hospitalization could clarify their true prognostic value. This work provides critical evidence on the limited usefulness of hematologic and biochemical indexes measured at admission as predictors of survival in cats with FPV, reinforcing the need for longitudinal studies and complementary parameters for better prognostic stratification. 000169935 540__ $$9info:eu-repo/semantics/embargoedAccess$$aby-nc-nd$$uhttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es 000169935 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion 000169935 700__ $$aFuertes Marí, Marta 000169935 700__ $$aMartinez Mas, Izarbe 000169935 700__ $$aDorado Whyte, Leticia 000169935 700__ $$aGranada Cires, Marta 000169935 700__ $$aGracia Polo, Sara 000169935 700__ $$aHernández Pérez, Sara 000169935 700__ $$aCánovas Carretero, Zara 000169935 700__ $$aChancellor Díez, Celia 000169935 700__ $$0(orcid)0000-0002-1204-4356$$ade Blas Giral, Ignacio$$uUniversidad de Zaragoza 000169935 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Sanidad Animal 000169935 7102_ $$11009$$2617$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Medicina y Cirugía Animal 000169935 773__ $$g317 (2026), 106619 [5 pp.]$$pVet. j.$$tVeterinary Journal$$x1090-0233 000169935 8564_ $$s1663967$$uhttps://zaguan.unizar.es/record/169935/files/texto_completo.pdf$$yPostprint$$zinfo:eu-repo/date/embargoEnd/2027-02-25 000169935 8564_ $$s1662183$$uhttps://zaguan.unizar.es/record/169935/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint$$zinfo:eu-repo/date/embargoEnd/2027-02-25 000169935 909CO $$ooai:zaguan.unizar.es:169935$$particulos$$pdriver 000169935 951__ $$a2026-03-06-14:50:51 000169935 980__ $$aARTICLE