169935 20260306154908.0 doi 10.1016/j.tvjl.2026.106619 sideral 148438 ART-2026-148438 eng Esteban Jiménez, Juan José Universidad de Zaragoza (orcid)0000-0001-7575-6599 Feline panleukopenia: Analysis of possible survival biomarkers 2026 Feline panleukopenia virus (FPV), also known as feline parvovirus, is a very common viral disease in cats, characterized by its high case fatality rate, for which the establishment of clear prognostic thresholds is complicated. The aim of this study was to evaluate the clinical relevance of different demographical, hematological, and biochemical variables and indexes obtained at hospital admission as potential prognostic factors for survival. A study was carried out of 58 cats diagnosed with FPV between 2017 and 2025 at the Veterinary Teaching Hospital of the University of Zaragoza. Variables analyzed included age, sex, hematocrit, counts of leukocytes, neutrophils, lymphocytes and platelets, neutrophil:lymphocyte ratio (NLR), platelet:lymphocyte ratio (PLR), albumin and potassium. The observed case fatality rate was 10.3% (6/58). No significant differences in survival were identified relative to age, sex, or the hematologic/biochemical indexes analyzed, although non-survivors tended to show lower hematocrit, albumin and neutrophil values together with relative lymphocytosis. These findings suggest that hematologic indexes such as NLR and PLR have limited utility in the feline species. Future studies with larger sample sizes and dynamic monitoring of biomarkers during hospitalization could clarify their true prognostic value. This work provides critical evidence on the limited usefulness of hematologic and biochemical indexes measured at admission as predictors of survival in cats with FPV, reinforcing the need for longitudinal studies and complementary parameters for better prognostic stratification. Access copy available to the general public Unrestricted info:eu-repo/semantics/embargoedAccess by-nc-nd https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Fuertes Marí, Marta Martinez Mas, Izarbe Dorado Whyte, Leticia Granada Cires, Marta Gracia Polo, Sara Hernández Pérez, Sara Cánovas Carretero, Zara Chancellor Díez, Celia de Blas Giral, Ignacio Universidad de Zaragoza (orcid)0000-0002-1204-4356 1009 773 Universidad de Zaragoza Dpto. Patología Animal Área Sanidad Animal 1009 617 Universidad de Zaragoza Dpto. Patología Animal Área Medicina y Cirugía Animal 317 (2026), 106619 [5 pp.] Vet. j. Veterinary Journal 1090-0233 1663967 http://zaguan.unizar.es/record/169935/files/texto_completo.pdf Postprint info:eu-repo/date/embargoEnd/2027-02-25 1662183 http://zaguan.unizar.es/record/169935/files/texto_completo.jpg?subformat=icon icon Postprint info:eu-repo/date/embargoEnd/2027-02-25 oai:zaguan.unizar.es:169935 articulos driver 2026-03-06-14:50:51 ARTICLE