000169980 001__ 169980
000169980 005__ 20260316092629.0
000169980 0247_ $$2doi$$a10.1002/jclp.70117
000169980 0248_ $$2sideral$$a148567
000169980 037__ $$aART-2026-148567
000169980 041__ $$aeng
000169980 100__ $$aPeláez, Trinidad
000169980 245__ $$aImpact of the Unified Protocol on Attenuated Psychotic Symptoms, Cognitive Biases and Cognitive Insight in Patients at Ultra High Risk (UHR) for Psychosis: Secondary Results of a Pilot Randomized Controlled Trial
000169980 260__ $$c2026
000169980 5060_ $$aAccess copy available to the general public$$fUnrestricted
000169980 5203_ $$aBackground and Hypothesis

Ultra high risk (UHR) for psychosis can have different clinical trajectories but the remission rates are only 51.9% after 3 years of follow-up. Deficits in metacognition are associated with severity of symptoms and poor response to treatment. We hypothesize that the Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders (UP) will have a positive effect on attenuated psychotic symptoms, cognitive biases and cognitive insight in UHR individuals.
Study Design

This article reports the secondary analyses of a pilot randomized controlled trial with 36 UHR participants assigned to either an online group intervention with UP plus Treatment as Usual (UP + TAU) or TAU alone. Assessments were conducted at baseline, post-intervention and 3-month follow-up and included the severity and distress of attenuated psychotic symptoms (CAARMS), cognitive biases (CBQp) and cognitive insight (BCIS).
Study Results

Significant differences were found in the evolution of the two groups in CAARMS distress scores in favor of the UP condition group. Significant differences in CBQp scores between the two groups were found in the two time assessments in favor of the UP group. No significant differences were found in cognitive insight.
Conclusions

The UP intervention showed promising effects in reducing distress related to attenuated psychotic symptoms and cognitive biases, but not in improving cognitive insight. Given the small sample size, which fell below the initial target, and the pilot nature of the study, these findings should be interpreted with caution and considered preliminary until replicated in adequately powered trials.
000169980 536__ $$9info:eu-repo/grantAgreement/ES/DGA/S31-23R
000169980 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
000169980 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000169980 700__ $$aLópez-Carrilero, Raquel
000169980 700__ $$aEspinosa, Victoria
000169980 700__ $$aBalsells, Sol
000169980 700__ $$aFusar-Poli, Paolo
000169980 700__ $$aOchoa, Susana
000169980 700__ $$0(orcid)0000-0002-7293-318X$$aOsma, Jorge$$uUniversidad de Zaragoza
000169980 7102_ $$14009$$2680$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Person.Eval.Trat.Psicoló.
000169980 773__ $$g(2026), [12 pp.]$$pJ. clin. psychol.$$tJOURNAL OF CLINICAL PSYCHOLOGY$$x0021-9762
000169980 8564_ $$s669771$$uhttps://zaguan.unizar.es/record/169980/files/texto_completo.pdf$$yVersión publicada
000169980 8564_ $$s2297702$$uhttps://zaguan.unizar.es/record/169980/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000169980 909CO $$ooai:zaguan.unizar.es:169980$$particulos$$pdriver
000169980 951__ $$a2026-03-16-08:16:11
000169980 980__ $$aARTICLE