Elevated interstitial fluid pressure promotes spheroid growth and reduces CAR-T therapeutic efficacy in solid tumors

Alamán-Díez, Pilar Ferrer-Royo, Silvia Oñate Salafranca, Carmen Martín Compaired, Pablo Balsas, Patricia Pardo, Julián García-Aznar, José Manuel González-Loyola, Alejandra Elevated interstitial fluid pressure promotes spheroid growth and reduces CAR-T therapeutic efficacy in solid tumors

Acta Biomater.

10.1016/j.actbio.2026.01.050 2026

2026