000170094 001__ 170094
000170094 005__ 20260318155254.0
000170094 0247_ $$2doi$$a10.1111/sms.70253
000170094 0248_ $$2sideral$$a148646
000170094 037__ $$aART-2026-148646
000170094 041__ $$aeng
000170094 100__ $$aConesa-Milian, Enric
000170094 245__ $$aHigh‐sensitivity cardiac troponin t release after the 20‐m shuttle run test in 733 healthy children and adolescents
000170094 260__ $$c2026
000170094 5060_ $$aAccess copy available to the general public$$fUnrestricted
000170094 5203_ $$aThis study aimed to assess the effect of exercise on high-sensitivity cardiac troponin T (hs-cTnT) concentrations in children and adolescents and to examine whether sex, maturational status, anthropometric characteristics, cardiorespiratory fitness, and physical activity influence the hs-cTnT response. In this trial 733 participants completed the 20-m shuttle run test. Venous blood samples were collected at rest and 3h postexercise to determine hs-cTnT concentrations. We included 296 girls and 437 boys (12.2±1.7 years; 40% girls). At baseline, 61% of participants had hs-cTnT values below the limit of detection (LoD), and 2.5% exceeded the upper reference limit (URL). Postexercise, 36% remained below LoD, while 7.5% exceeded the URL. Overall, hs-cTnT increased from baseline to 3h postexercise in 56.2% of participants. Linear mixed-effects models showed a significant main effect of time (β=−0.42, 95% CI 0.35–0.49; p<0.01) and no main effect of sex (p=0.85), although a small but significant time×sex interaction was observed (β=−0.11, 95% CI −0.20 to −0.02; p=0.021), indicating a slightly greater exercise-induced increase in girls. Additional significant time×covariate interactions were identified for maturational, anthropometric, and fitness-related variables. However, these factors together explained only a small proportion of the overall variability in hs-cTnT response. Consequently, the 20-m shuttle run test induces a significant increase in hs-cTnT concentrations in children and adolescents. Exercise-induced hs-cTnT release is common but highly heterogeneous, and is only partly explained by sex, maturational, anthropometric, and fitness-related factors, suggesting an important contribution of individual-specific determinants not captured by conventional variables.
000170094 536__ $$9info:eu-repo/grantAgreement/ES/AEI/PID2020-117932RB-I00
000170094 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
000170094 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000170094 700__ $$aBatalla-Gavaldà, Abraham
000170094 700__ $$aHernández-González, Vicenç
000170094 700__ $$0(orcid)0000-0002-9304-3709$$aLópez-Laval, Isaac$$uUniversidad de Zaragoza
000170094 700__ $$aCorbi, Francesc
000170094 700__ $$aCirer-Sastre, Rafel
000170094 700__ $$0(orcid)0000-0003-2644-9386$$aLegaz-Arrese, Alejandro$$uUniversidad de Zaragoza
000170094 700__ $$aReverter-Masia, Joaquin
000170094 7102_ $$11006$$2245$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Educación Física y Depor.
000170094 773__ $$g36, 3 (2026), [9 pp.]$$pScand. j. med. sci. sports$$tScandinavian Journal of Medicine and Science in Sports$$x0905-7188
000170094 8564_ $$s761460$$uhttps://zaguan.unizar.es/record/170094/files/texto_completo.pdf$$yVersión publicada
000170094 8564_ $$s2566312$$uhttps://zaguan.unizar.es/record/170094/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000170094 909CO $$ooai:zaguan.unizar.es:170094$$particulos$$pdriver
000170094 951__ $$a2026-03-18-13:52:09
000170094 980__ $$aARTICLE