000170115 001__ 170115
000170115 005__ 20260318155255.0
000170115 0247_ $$2doi$$a10.1016/j.annepidem.2026.110064
000170115 0248_ $$2sideral$$a148654
000170115 037__ $$aART-2026-148654
000170115 041__ $$aeng
000170115 100__ $$aVitoratou, Dimitra-Irinna
000170115 245__ $$aThe revised-FINDRISC: A tool for type 2 diabetes risk screening across diverse populations incorporating sociodemographic indicators
000170115 260__ $$c2026
000170115 5060_ $$aAccess copy available to the general public$$fUnrestricted
000170115 5203_ $$aAim
Τo develop a revised version of the FINDRISC tailored to improve the identification of individuals at high risk for type 2 diabetes (T2D) across diverse populations.
Methods
The revised-FINDRISC was developed using pooled harmonized baseline data from the multinational Feel4Diabetes (NCT02393872; N = 3526) and DigiCare4You (NCT05648383; N = 2156) studies. Validation utilized data from the 20-year ATTICA cohort study in Greece. Original FINDRISC components were analyzed using Fisher’s Linear Discriminant Analysis followed by supervised stepwise logistic regression to identify significant T2D cross-sectional predictors. The revised-FINDRISC was developed by re-scoring or excluding original items and incorporating new predictors, generating an integer-based score to enhance usability.
Results
The revised-FINDRISC significantly improved accuracy in identifying current T2D risk over the original, with an overall AUC of 0.911(95%CI: 0.901,0.922) versus 0.832(0.815,0.846). When stratified by country economic classification, the revised score outperformed the original across all groups: LMICs: 0.881(0.864,0.898) vs. 0.815(0.793,0.837), South European-HICs: 0.891(0.867,0.916) vs. 0.839(0.811,0.869), and North European-HICs: 0.921(0.872,0.971) vs. 0.844(0.742,0.949). A clinical threshold score of 13/24 in the revised-FINDRISC offers optimal sensitivity and specificity for identifying individuals at risk of T2D.
Conclusion
Enhanced with demographic, socio-economic, and clinical factors, the revised-FINDRISC potentially represents a substantive advancement in T2D screening, supporting early detection and targeted prevention.
000170115 536__ $$9info:eu-repo/grantAgreement/EC/H2020/643708/EU/Developing and implementing a community-based intervention to create a more supportive social and physical environment for lifestyle changes to prevent diabetes in vulnerable families across Europe/Feel4Diabetes$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 643708-Feel4Diabetes$$9info:eu-repo/grantAgreement/EC/H2020/945246 /EU/An intersectoral innovative solution involving DIGItal tools, empowering families and integrating community CARE services for the prevention and management of type 2 diabetes and hypertension/DigiCare4You$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 945246 -DigiCare4You
000170115 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000170115 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000170115 700__ $$aDimakopoulou, Konstantina
000170115 700__ $$aMavrogianni, Christina
000170115 700__ $$aKaraglani, Eva
000170115 700__ $$aArgyropoulou, Matzourana
000170115 700__ $$aCardon, Greet
000170115 700__ $$aUsheva, Natalya
000170115 700__ $$aIotova, Violeta
000170115 700__ $$aTankova, Tsvetalina
000170115 700__ $$0(orcid)0000-0002-2956-4219$$aGiménez-Legarre, Natalia
000170115 700__ $$0(orcid)0000-0003-0454-653X$$aMoreno, Luis A.$$uUniversidad de Zaragoza
000170115 700__ $$aToti, Florian
000170115 700__ $$aMakrilakis, Konstantinos
000170115 700__ $$aDoracaj, Ditila
000170115 700__ $$aImre, Rurik
000170115 700__ $$aTorzsa, Péter
000170115 700__ $$aLindström, Jaana
000170115 700__ $$aPanagiotakos, Demosthenes
000170115 700__ $$aManios, Yannis
000170115 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000170115 773__ $$g117 (2026), 110064 [10 pp.]$$pAnn. epidemiol.$$tANNALS OF EPIDEMIOLOGY$$x1047-2797
000170115 8564_ $$s2558757$$uhttps://zaguan.unizar.es/record/170115/files/texto_completo.pdf$$yVersión publicada
000170115 8564_ $$s2405070$$uhttps://zaguan.unizar.es/record/170115/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000170115 909CO $$ooai:zaguan.unizar.es:170115$$particulos$$pdriver
000170115 951__ $$a2026-03-18-13:52:37
000170115 980__ $$aARTICLE