170115 20260318155255.0 doi 10.1016/j.annepidem.2026.110064 sideral 148654 ART-2026-148654 eng Vitoratou, Dimitra-Irinna The revised-FINDRISC: A tool for type 2 diabetes risk screening across diverse populations incorporating sociodemographic indicators 2026 Aim Τo develop a revised version of the FINDRISC tailored to improve the identification of individuals at high risk for type 2 diabetes (T2D) across diverse populations. Methods The revised-FINDRISC was developed using pooled harmonized baseline data from the multinational Feel4Diabetes (NCT02393872; N = 3526) and DigiCare4You (NCT05648383; N = 2156) studies. Validation utilized data from the 20-year ATTICA cohort study in Greece. Original FINDRISC components were analyzed using Fisher’s Linear Discriminant Analysis followed by supervised stepwise logistic regression to identify significant T2D cross-sectional predictors. The revised-FINDRISC was developed by re-scoring or excluding original items and incorporating new predictors, generating an integer-based score to enhance usability. Results The revised-FINDRISC significantly improved accuracy in identifying current T2D risk over the original, with an overall AUC of 0.911(95%CI: 0.901,0.922) versus 0.832(0.815,0.846). When stratified by country economic classification, the revised score outperformed the original across all groups: LMICs: 0.881(0.864,0.898) vs. 0.815(0.793,0.837), South European-HICs: 0.891(0.867,0.916) vs. 0.839(0.811,0.869), and North European-HICs: 0.921(0.872,0.971) vs. 0.844(0.742,0.949). A clinical threshold score of 13/24 in the revised-FINDRISC offers optimal sensitivity and specificity for identifying individuals at risk of T2D. Conclusion Enhanced with demographic, socio-economic, and clinical factors, the revised-FINDRISC potentially represents a substantive advancement in T2D screening, supporting early detection and targeted prevention. Access copy available to the general public Unrestricted info:eu-repo/grantAgreement/EC/H2020/643708/EU/Developing and implementing a community-based intervention to create a more supportive social and physical environment for lifestyle changes to prevent diabetes in vulnerable families across Europe/Feel4Diabetes This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 643708-Feel4Diabetes info:eu-repo/grantAgreement/EC/H2020/945246 /EU/An intersectoral innovative solution involving DIGItal tools, empowering families and integrating community CARE services for the prevention and management of type 2 diabetes and hypertension/DigiCare4You This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 945246 -DigiCare4You info:eu-repo/semantics/openAccess by https://creativecommons.org/licenses/by/4.0/deed.es info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Dimakopoulou, Konstantina Mavrogianni, Christina Karaglani, Eva Argyropoulou, Matzourana Cardon, Greet Usheva, Natalya Iotova, Violeta Tankova, Tsvetalina Giménez-Legarre, Natalia (orcid)0000-0002-2956-4219 Moreno, Luis A. Universidad de Zaragoza (orcid)0000-0003-0454-653X Toti, Florian Makrilakis, Konstantinos Doracaj, Ditila Imre, Rurik Torzsa, Péter Lindström, Jaana Panagiotakos, Demosthenes Manios, Yannis 1006 255 Universidad de Zaragoza Dpto. Fisiatría y Enfermería Área Enfermería 117 (2026), 110064 [10 pp.] Ann. epidemiol. ANNALS OF EPIDEMIOLOGY 1047-2797 2558757 http://zaguan.unizar.es/record/170115/files/texto_completo.pdf Versión publicada 2405070 http://zaguan.unizar.es/record/170115/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:170115 articulos driver 2026-03-18-13:52:37 ARTICLE