Multisite phosphorylation of the AML-linked C-terminal of nucleophosmin (NPM1) orchestrates protein stability, DNA binding and charge block-driven phase separation

Rivero-García, Pablo Giner-Arroyo, Rafael L Tamargo-Azpilicueta, Joaquín Telfer, Abbey Frezza , Elisa Velázquez-Campoy, Adrián Díaz-Moreno, Sofía De la Rosa, Miguel A. Díaz-Moreno, Irene Multisite phosphorylation of the AML-linked C-terminal of nucleophosmin (NPM1) orchestrates protein stability, DNA binding and charge block-driven phase separation

Nucleic acids res.

10.1093/nar/gkag165 2026

2026