000170176 001__ 170176
000170176 005__ 20260407115449.0
000170176 0247_ $$2doi$$a10.1016/j.sab.2025.107307
000170176 0248_ $$2sideral$$a148713
000170176 037__ $$aART-2025-148713
000170176 041__ $$aeng
000170176 100__ $$0(orcid)0000-0002-7931-3901$$aAbad-Álvaro, Isabel$$uUniversidad de Zaragoza
000170176 245__ $$aSize detection limits in single particle inductively coupled plasma mass spectrometry: Reconsidering the selection of dwell times
000170176 260__ $$c2025
000170176 5060_ $$aAccess copy available to the general public$$fUnrestricted
000170176 5203_ $$aPerformance of single particle inductively coupled plasma mass spectrometry (SP-ICP-MS) methods is constrained by the characteristics of the instrumentation. The commercial availability of fast data acquisition quadrupole instruments, which allow the use of dwell times in the microsecond range rather than being restricted to milliseconds, was expected to improve the performance of the technique. When data acquisition frequency is increased, individual particles are recorded as transient signals consisting of multiple-reading events instead of one-reading pulses. Since particle events must be detected above the baseline noise, the highest intensity reading of a transient signal becomes a relevant parameter whose value decreases with decreasing dwell time, as the total intensity of a particle event is independent of the number of readings per event and thus of the selected dwell time. In this work, the effect of dwell time on the attainable size detection limits has been reconsidered, achieving minimum size detection limits when dwell times in the range of 200–500 μs were used, regardless of the baseline level. At such dwell times, particle events from small nanoparticles (e.g., 2–3 times the size detection limit) were recorded within 1–2 readings despite the duration of particle events, which was modified working in both standard and gas reaction modes. Under these conditions, free and proprietary software capable of handling multiple-reading events allowed to process successfully the SP-ICP-MS data independently of the dwell time applied.
000170176 536__ $$9info:eu-repo/grantAgreement/ES/DGA/E29-23R$$9info:eu-repo/grantAgreement/ES/MICINN/PID2021-123203OB-I00$$9info:eu-repo/grantAgreement/ES/NextGenerationEU/MZ-240621
000170176 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttps://creativecommons.org/licenses/by-nc/4.0/deed.es
000170176 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000170176 700__ $$0(orcid)0000-0002-1856-2058$$aBolea, Eduardo$$uUniversidad de Zaragoza
000170176 700__ $$0(orcid)0000-0002-4169-0357$$aLaborda, Francisco$$uUniversidad de Zaragoza
000170176 7102_ $$12009$$2750$$aUniversidad de Zaragoza$$bDpto. Química Analítica$$cÁrea Química Analítica
000170176 773__ $$g236 (2025), 107307 [8 p.]$$pSpectrochim. acta, Part B: Atom. spectrosc.$$tSpectrochimica Acta - Part B Atomic Spectroscopy$$x0584-8547
000170176 8564_ $$s3031690$$uhttps://zaguan.unizar.es/record/170176/files/texto_completo.pdf$$yVersión publicada
000170176 8564_ $$s2589290$$uhttps://zaguan.unizar.es/record/170176/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000170176 909CO $$ooai:zaguan.unizar.es:170176$$particulos$$pdriver
000170176 951__ $$a2026-03-26-14:31:05
000170176 980__ $$aARTICLE