000170211 001__ 170211 000170211 005__ 20260407115449.0 000170211 0247_ $$2doi$$a10.1016/j.cmi.2026.01.012 000170211 0248_ $$2sideral$$a148743 000170211 037__ $$aART-2026-148743 000170211 041__ $$aeng 000170211 100__ $$aAlbers, Bianca 000170211 245__ $$aGuiding principles for implementing ESCMID clinical practice guidelines 000170211 260__ $$c2026 000170211 5203_ $$aBackground. Clinical practice guidelines (CPGs) must be effectively implemented to result in meaningful improvements in patient care, support evidence-based decision-making, and drive high-quality, standardized medical practice. Objectives. This paper is a guide to current best practices for quality implementation of CPGs, with a focus on the European Society of Clinical Microbiology and Infectious Diseases guidelines for the prevention, diagnosis, and management of infection. Sources. The guide is informed by implementation science and based on the RE-AIM/PRISM implementation framework, one of the most used frameworks for planning and monitoring research-supported change in healthcare. Content. A systematic approach to CPG implementation should be guided by three key principles commonly acknowledged in implementation science and reflected in the RE-AIM/PRISM model: (1) understanding the context into which the guideline will be embedded, (2) tailoring the guideline and its implementation to this context, and (3) monitoring guideline implementation. Implications. To improve the applicability, effectiveness, and sustainability of novel CPGs, future advancements should prioritize their intentional, well-planned dissemination and implementation, and the rigorous evaluation of CPG outcomes. 000170211 540__ $$9info:eu-repo/semantics/closedAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/ 000170211 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000170211 700__ $$aNagavci, Blin 000170211 700__ $$aJoean, Oana 000170211 700__ $$aTschudin Sutter, Sarah 000170211 700__ $$aTacconelli, Evelina 000170211 700__ $$aPaul, Mical 000170211 700__ $$aLangendam, Miranda 000170211 700__ $$aKostyanev, Tomislav 000170211 700__ $$aMolina, Jose 000170211 700__ $$aStahl, Jean Paul 000170211 700__ $$0(orcid)0000-0002-9600-8116$$aPaño Pardo, Jose Ramon$$uUniversidad de Zaragoza 000170211 700__ $$aGkrania-Klotsas, Effrossyni 000170211 700__ $$aHassoun-Kheir, Nasreen 000170211 700__ $$aClack, Lauren 000170211 700__ $$aScudeller, Luigia 000170211 700__ $$aZervos, Marcus 000170211 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina 000170211 773__ $$g(2026), 8 pp.$$pClin. microbiol. infect.$$tClinical Microbiology and Infection$$x1198-743X 000170211 8564_ $$s1317767$$uhttps://zaguan.unizar.es/record/170211/files/texto_completo.pdf$$yVersión publicada 000170211 8564_ $$s2490465$$uhttps://zaguan.unizar.es/record/170211/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000170211 909CO $$ooai:zaguan.unizar.es:170211$$particulos$$pdriver 000170211 951__ $$a2026-03-26-14:31:47 000170211 980__ $$aARTICLE