000170214 001__ 170214
000170214 005__ 20260407115449.0
000170214 0247_ $$2doi$$a10.1007/s00431-026-06844-3
000170214 0248_ $$2sideral$$a148767
000170214 037__ $$aART-2026-148767
000170214 041__ $$aeng
000170214 100__ $$aLarruy-García, A.
000170214 245__ $$aA Mediterranean lifestyle obesity prevention intervention in preschoolers at risk: MELI-POP Study—a randomized controlled trial
000170214 260__ $$c2026
000170214 5060_ $$aAccess copy available to the general public$$fUnrestricted
000170214 5203_ $$aThis study aimed to determine whether a Mediterranean lifestyle intervention, including diet and physical activity (PA), influences body composition and cardiovascular risk factors in preschoolers at risk of obesity due to family history. A parallel RCT was conducted in three Spanish cities, enrolling 206 children aged 3.0–6.9 years with normal weight or overweight and at least one parent with overweight or obesity. Participants were recruited from health centers, hospitals, and schools, and randomly assigned to either a Mediterranean lifestyle intervention or a control group. The intervention included provision of fish and olive oil, monthly nutrition education, and twice-weekly PA sessions, while the control group received general child health advice unrelated to diet or exercise. After 12 months, 170 children completed the study (17.5% dropout). Outcomes included BMI, fat mass index (FMI), and respective z-scores (primary), as well as waist-to-height ratio, blood pressure, lipid profile, glucose, and insulin (secondary). At baseline, no significant differences were observed between groups. Per-protocol analysis showed significant differences in BMI and FMI (kg/m2 and z-score) between the intervention and control groups among girls, but not among boys. Intention-to-treat analysis confirmed these findings in girls, showing significant changes in BMI (− 0.68 kg/m2) and BMI z-score (− 0.34) compared with the control group. In both per-protocol and intention-to-treat analyses, no significant between-group differences were observed in changes in cardiovascular risk factors.
Conclusion: A Mediterranean lifestyle intervention may benefit body composition changes in preschool girls at risk of obesity; larger studies are needed to confirm these sex-specific results.
000170214 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII/PI18-00666$$9info:eu-repo/grantAgreement/ES/ISCIII/PI18-00930$$9info:eu-repo/grantAgreement/ES/ISCIII/PI22-00912$$9info:eu-repo/grantAgreement/ES/ISCIII/PI22-01337
000170214 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000170214 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000170214 700__ $$0(orcid)0000-0001-6173-5850$$aMiguel-Etayo, P. de
000170214 700__ $$aGil-Campos, M.
000170214 700__ $$0(orcid)0000-0002-3007-302X$$aEsteban, L. M.
000170214 700__ $$aPicáns-Leis, R.
000170214 700__ $$aPastor-Villaescusa, B.
000170214 700__ $$aVázquez-Cobela, R.
000170214 700__ $$aFlores-Rojas, K.
000170214 700__ $$aLeis, R.
000170214 700__ $$aMoreno, L. A.
000170214 773__ $$g185, 207 (2026), 1-12$$pEur. j. pediatr.$$tEuropean Journal of Pediatrics$$x0340-6199
000170214 8564_ $$s1291170$$uhttps://zaguan.unizar.es/record/170214/files/texto_completo.pdf$$yVersión publicada
000170214 8564_ $$s2273134$$uhttps://zaguan.unizar.es/record/170214/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000170214 909CO $$ooai:zaguan.unizar.es:170214$$particulos$$pdriver
000170214 951__ $$a2026-03-26-14:31:50
000170214 980__ $$aARTICLE