170413 20260420103355.0 doi 10.1016/j.molliq.2026.129573 sideral 148955 ART-2026-148955 eng Gavín, Ana Oleic acid: geraniol or cinnamyl alcohol hydrophobic mixtures: thermophysical properties and quercetin solubility 2026 The low solubility of drugs and nutraceuticals in water decreases their bioavailability, which poses a serious challenge to the biotechnology industry. To improve this, several mixtures have been proposed. Here, the solubility and antioxidant capacity of quercetin in binary mixtures of oleic acid with geraniol and cinnamyl alcohol are determined. As a preliminary step, phase changes and thermophysical properties are discussed and modelled with the PC-SAFT EoS. The densities were between 6% at 283.15 K and 11% at 338.15 K lower than those of water. The surface tensions and viscosities were moderate and also decreased as the temperature increased. The equation of state correctly predicted the density and heat capacity, with average deviations less than 0.32% and 1.9%, respectively. The solubility of quercetin was favored in both mixtures. A synergistic effect on the antioxidant capacity was observed in the mixture with geraniol, which was the least compact. Access copy available to the general public Unrestricted info:eu-repo/grantAgreement/ES/DGA/E31-23R-PLATON info:eu-repo/semantics/openAccess by-nc-nd https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Juan, Daniel Muñoz-Embid, José Universidad de Zaragoza (orcid)0000-0002-8354-7436 Haftbaradaran Esfahani, Mohammadreza Lafuente, Carlos Universidad de Zaragoza (orcid)0000-0003-3632-6822 Artal, Manuela Universidad de Zaragoza (orcid)0000-0003-1810-9488 2012 755 Universidad de Zaragoza Dpto. Química Física Área Química Física 454 (2026), 129573 [12 pp.] J. mol. liq. Journal of Molecular Liquids 0167-7322 2724202 http://zaguan.unizar.es/record/170413/files/texto_completo.pdf Versión publicada 2727517 http://zaguan.unizar.es/record/170413/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:170413 articulos driver 2026-04-18-10:49:06 ARTICLE