170461 20260422085545.0 doi 10.1007/s10840-026-02288-9 sideral 148970 ART-2026-148970 eng Sales-Belles, Clara Universidad de Zaragoza Real-time assessment of inter and intraventricular synchrony in cardiac resynchronization therapy with left bundle branch pacing using ECGi and low-frequency QRS analysis 2026 Introduction: Left bundle branch pacing (LBBP) is an alternative to conventional biventricular pacing for cardiac resynchronization therapy (CRT). Methods: A 76-year-old male was referred for CRT via left bundle branch pacing (LBBP). We present the real-time characterization of the transition from intrinsic left bundle branch block (LBBB) to sequential pacing modalities: right ventricular septal pacing (RVSP), left ventricular septal pacing (LVSP), and finally LBBP. Epicardial activation maps from electrocardiographic imaging (ECGi) and low-frequency (LF) QRS analysis were used to provide complementary insights into interand intraventricular synchrony. Results: LVSP, LBBP, and anodal capture improved activation compared with baseline, with LBBP achieving the greatest improvements in interventricular and LV intraventricular synchrony despite higher RV dispersion. Conclusion: These findings highlight ECGi and LF QRS as valuable tools to guide CRT. Access copy available to the general public Unrestricted info:eu-repo/grantAgreement/ES/AEI/PID2021-128972OA-I00 info:eu-repo/grantAgreement/ES/DGA/LMP 94-21 info:eu-repo/grantAgreement/ES/DGA/T39-23R info:eu-repo/grantAgreement/ES/MICINN/AEI/CNS2022-135899 info:eu-repo/grantAgreement/ES/MICINN/PID2022-140556OB-I00 info:eu-repo/grantAgreement/ES/MICINN/RYC2019-027420-I info:eu-repo/grantAgreement/EUR/MICINN/TED2021-130459B-I00 info:eu-repo/semantics/openAccess by https://creativecommons.org/licenses/by/4.0/deed.es info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Mincholé, Ana Universidad de Zaragoza (orcid)0000-0003-3183-4107 Cabrera-Ramos, Mercedes Universidad de Zaragoza Melero-Polo, Jorge Universidad de Zaragoza Pueyo, Esther Universidad de Zaragoza (orcid)0000-0002-1960-407X Ramos Maqueda, Javier Universidad de Zaragoza 1007 610 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Medicina 5008 800 Universidad de Zaragoza Dpto. Ingeniería Electrón.Com. Área Teoría Señal y Comunicac. (2026), [6 pp.] J. Interv. Card. Electrophysiol. JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY 1383-875X 2662310 http://zaguan.unizar.es/record/170461/files/texto_completo.pdf Versión publicada 2217702 http://zaguan.unizar.es/record/170461/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:170461 articulos driver 2026-04-22-08:32:54 ARTICLE