170479 20260422085545.0 doi 10.3390/vetsci13040389 sideral 148969 ART-2026-148969 eng Quilez, Pablo Universidad de Zaragoza (orcid)0009-0003-9757-3840 Diagnostic Performance of Infrared Nasal Thermography for the Detection of Enzootic Nasal Adenocarcinoma in Goats 2026 Enzootic nasal adenocarcinoma is a contagious neoplasm of goats for which early antemortem diagnosis remains challenging under field conditions. This study evaluated the diagnostic accuracy of infrared nasal thermography for detecting the disease using histopathology as the reference standard. Eighty-six goats from a dairy herd with confirmed enzootic nasal adenocarcinoma were examined by infrared thermography one day prior to slaughter under standardized environmental conditions. Thermal images of the ethmoidal region were qualitatively assessed for asymmetry or focal hyperthermia. Following slaughter, all heads underwent systematic necropsy and bilateral histopathological examination. Twenty-three goats (26.7%) were histologically confirmed as positive with confirmation by RT-PCR (Reverse Transcriptase Polymerase Chain Reaction) from tissue samples. Infrared thermography showed a sensitivity of 82.6% and a specificity of 90.5%, with an overall diagnostic accuracy of 88.4%. Positive and negative predictive values were 76.0% and 93.4%, respectively. Agreement between thermography and histopathology was substantial (Cohen’s κ = 0.711; p < 0.001). Although thermography did not achieve the specificity of macroscopic post-mortem examination, its non-invasive and rapid nature supports its potential as a preliminary complementary antemortem screening approach, although its applicability at herd level requires validation in broader and more representative populations. Access copy available to the general public Unrestricted info:eu-repo/grantAgreement/ES/DGA/AR15-23R info:eu-repo/semantics/openAccess by https://creativecommons.org/licenses/by/4.0/deed.es info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Ruiz de Arcaute, Marta Universidad de Zaragoza (orcid)0000-0002-7655-2472 de las Heras, Marcelo Lacasta, Delia Universidad de Zaragoza (orcid)0000-0002-7822-6646 Guallar, David Universidad de Zaragoza Balado, Javier González, José María Hedman, Carlos (orcid)0000-0002-0827-110X Benito, Alfredo Ruiz, Héctor Universidad de Zaragoza (orcid)0000-0002-8474-2831 Ortín, Aurora Universidad de Zaragoza (orcid)0000-0002-0313-5926 1009 773 Universidad de Zaragoza Dpto. Patología Animal Área Sanidad Animal 1009 617 Universidad de Zaragoza Dpto. Patología Animal Área Medicina y Cirugía Animal 13, 4 (2026), 389 [10 pp.] Veterinary Sciences 2306-7381 1411375 http://zaguan.unizar.es/record/170479/files/texto_completo.pdf Versión publicada 2576049 http://zaguan.unizar.es/record/170479/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:170479 articulos driver 2026-04-22-08:33:17 ARTICLE