000170482 001__ 170482
000170482 005__ 20260422085546.0
000170482 0247_ $$2doi$$a10.3389/fvets.2026.1789622
000170482 0248_ $$2sideral$$a148978
000170482 037__ $$aART-2026-148978
000170482 041__ $$aeng
000170482 100__ $$aSánchez-Mora, Patricia
000170482 245__ $$aDetection and genetic characterization of Crimean-Congo hemorrhagic fever virus in ticks from western Spain (2017, 2020-2024)
000170482 260__ $$c2026
000170482 5060_ $$aAccess copy available to the general public$$fUnrestricted
000170482 5203_ $$aIntroduction: Crimean-Congo hemorrhagic fever virus (CCHFV) was first detected in Spain in ticks collected from red deer in southwestern Cáceres. Since then, this region, established as endemic, has been the focus of several surveillance studies. However, updated data on viral circulation in this area remain limited.
Materials and Methods: We conducted a retrospective surveillance study to assess the presence and genetic diversity of CCHFV in ticks collected in central and southern Cáceres over multiple years (2017 and 2020–2024). A total of 3,183 ticks, grouped into 1,569 pools, were collected from wild ungulates, livestock, domestic animals and vegetation, and analyzed by two PCR methods. Positive pools were characterized by Sanger sequencing.
Results: CCHFV was exclusively detected in Hyalomma lusitanicum ticks, with an overall infection rate of 1.54% (95% CI: 1.14–2.03). Most positive pools originated from wild ungulates, particularly red deer. Genetic analysis revealed the circulation of two CCHFV genotypes, predominantly genotype III.
Discussion: The detection of CCHFV in ticks collected over multiple years supports the sustained circulation of the virus in southwestern Cáceres. Our findings also reinforce the key role of H. lusitanicum as the main vector maintaining the virus in wild ungulates and underscore the genetic diversity of circulating strains and the importance of using multiple molecular methods. These results emphasize the need for continuous surveillance inendemic areas to monitor viral circulation and assess animal and public health risks.
000170482 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII-AESI/PI21CIII-00014$$9info:eu-repo/grantAgreement/ES/ISCIII-AESI/PI25CIII-00042$$9info:eu-repo/grantAgreement/ES/ISCIII/CB21-13-00110
000170482 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000170482 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000170482 700__ $$aHabela, Miguel A.
000170482 700__ $$adel Peso, Teresa
000170482 700__ $$aGrande Ávila, Ana Candela
000170482 700__ $$aGarcía López, Ana María
000170482 700__ $$aMata García Soldado, Jennifer
000170482 700__ $$aTapia, María M.
000170482 700__ $$aMolero, Francisca
000170482 700__ $$aHerrero, Laura
000170482 700__ $$aOlmeda, A. Sonia
000170482 700__ $$aValcárcel, Félix
000170482 700__ $$0(orcid)0000-0001-7483-046X$$aEstrada-Peña, Agustín
000170482 700__ $$aNegredo, Anabel
000170482 700__ $$aSánchez-Seco, María Paz
000170482 773__ $$g13 (2026), [10 pp.]$$pFront. vet. sci.$$tFrontiers in Veterinary Science$$x2297-1769
000170482 8564_ $$s2086546$$uhttps://zaguan.unizar.es/record/170482/files/texto_completo.pdf$$yVersión publicada
000170482 8564_ $$s2389490$$uhttps://zaguan.unizar.es/record/170482/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000170482 909CO $$ooai:zaguan.unizar.es:170482$$particulos$$pdriver
000170482 951__ $$a2026-04-22-08:33:21
000170482 980__ $$aARTICLE