000171134 001__ 171134
000171134 005__ 20260515163944.0
000171134 0247_ $$2doi$$a10.1007/s00198-015-3159-1
000171134 0248_ $$2sideral$$a92302
000171134 037__ $$aART-2015-92302
000171134 041__ $$aeng
000171134 100__ $$0(orcid)0000-0001-8500-1667$$aMatute-Llorente, A.$$uUniversidad de Zaragoza
000171134 245__ $$aEffect of whole body vibration training on bone mineral density and bone quality in adolescents with Down syndrome: a randomized controlled trial
000171134 260__ $$c2015
000171134 5203_ $$aSummary
Adolescents with Down syndrome (DS) have poorer bone health than their peers without DS. Twenty-five adolescents with DS were randomly assigned to whole-body vibration training (WBV) or control groups. The results indicate that a 20-week WBV might be useful to improve subtotal bone mineral content and density in adolescents with DS.
Introduction
This study aims to determine the effects of 20 weeks of whole body vibration training (WBV) on bone mineral content (BMC), density (BMD), and structure variables in adolescents with Down syndrome (DS).
Methods
This randomized controlled trial of 25 adolescents (12–18 years) with DS (8 females) generated 2 non-equal groups, WBV group (n = 11) and CON group (n = 14). Using an efficacy analysis, the primary outcomes were BMC and BMD by dual-energy X-ray absorptiometry and the secondary were bone structure variables by peripheral quantitative computed tomography. A synchronous vibration platform (PowerPlate®) was used (3/week, 10 repetitions (30–60 s) 1-min rest, frequency of 25–30 Hz, and peak-to-peak displacement of 2 mm (peak acceleration 2.5–3.6 g)).
Results
WBV group improved whole body BMC 2.8 %, 95 % CI [3.5, 2.1], subtotal area, BMC, and BMD by 2.8, 4.8, and 2 %, respectively, 95 % confidence intervals (CIs) [3.4, 2.1], [6.5, 3.1], and [2.8, 1.1], respectively (all, p < 0.05), showing group by time interactions in BMC and BMD (both p < 0.05). Lumbar spine BMC and BMD also increased in the WBV group by 6.6 and 3.3 % both p < 0.05, 95 % CIs [8.6, 4.7], and [4.9, 1.7], respectively. Regarding bone structure, WBV group showed improvements in tibial BMC at 4 % (2.9 %, 95 % CI [3.0, 2.8]) and in volumetric BMD (vBMD), cortical vBMD, and cortical thickness at 66 % of the radius (by 7.0, 2.4, and 10.9 %; 95 % CIs [7.4, 6.7], [2.6, 2.3], and [12.4, 9.3], respectively) (all, p < 0.05).
Conclusions
A 20-week WBV, with this protocol, might be useful to improve subtotal BMC and BMD in adolescents with DS.
000171134 536__ $$9info:eu-repo/grantAgreement/ES/MEC/AP-2012-02854$$9info:eu-repo/grantAgreement/ES/MICINN/DEP2009-09183
000171134 540__ $$9info:eu-repo/semantics/closedAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000171134 590__ $$a3.445$$b2015
000171134 591__ $$aENDOCRINOLOGY & METABOLISM$$b45 / 131 = 0.344$$c2015$$dQ2$$eT2
000171134 592__ $$a1.48$$b2015
000171134 593__ $$aMedicine (miscellaneous)$$c2015$$dQ1
000171134 593__ $$aEndocrinology, Diabetes and Metabolism$$c2015$$dQ1
000171134 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000171134 700__ $$0(orcid)0000-0002-1132-5906$$aGonzález-Agüero, A.$$uUniversidad de Zaragoza
000171134 700__ $$0(orcid)0000-0001-6492-2512$$aGómez-Cabello, A.
000171134 700__ $$aOlmedillas, H.
000171134 700__ $$0(orcid)0000-0002-4303-4097$$aVicente-Rodríguez, G.$$uUniversidad de Zaragoza
000171134 700__ $$0(orcid)0000-0002-7215-6931$$aCasajús, J. A.$$uUniversidad de Zaragoza
000171134 7102_ $$11006$$2245$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Educación Física y Depor.
000171134 773__ $$g26, 10 (2015), 2449-2459$$pOsteoporos. int.$$tOSTEOPOROSIS INTERNATIONAL$$x0937-941X
000171134 8564_ $$s584824$$uhttps://zaguan.unizar.es/record/171134/files/texto_completo.pdf$$yVersión publicada
000171134 8564_ $$s2021877$$uhttps://zaguan.unizar.es/record/171134/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000171134 909CO $$ooai:zaguan.unizar.es:171134$$particulos$$pdriver
000171134 951__ $$a2026-05-15-14:53:28
000171134 980__ $$aARTICLE