000171179 001__ 171179
000171179 005__ 20260515163945.0
000171179 0247_ $$2doi$$a10.1038/s41390-026-04889-6
000171179 0248_ $$2sideral$$a149156
000171179 037__ $$aART-2026-149156
000171179 041__ $$aeng
000171179 100__ $$aGheorghita, Irina
000171179 245__ $$aAssociation between dietary patterns and cardiometabolic health in children: findings from the Childhood Obesity Risk Assessment Longitudinal Study (CORALS) cohort
000171179 260__ $$c2026
000171179 5060_ $$aAccess copy available to the general public$$fUnrestricted
000171179 5203_ $$aBackground: Dietary habits influence health from childhood, with effects that may persist throughout life. This study aimed to investigate the association between dietary patterns and cardiometabolic risk markers in early childhood. Methods: A cross-sectional analysis was performed within the Childhood Obesity Risk Assessment Longitudinal Study (CORALS) cohort. Diet was assessed by a validated food frequency questionnaire. Dietary patterns were extracted using exploratory factor analysis. Cardiometabolic risk was analysed through internal z-scores, body mass index (BMIz), systolic blood pressure, HDL cholesterol (HDLz), triglycerides and HOMA-IR, and multi-adjusted linear regression models were performed. Results: The analysis included 1426 participants (median age 4.95 years). Two dietary patterns (DPs) were identified: “Core-foods DP” (high in vegetables, fruits, nuts, legumes, fish and white meat) and “Poor-quality DP” (rich in flavoured dairy products, processed meat, pastries, sweets, snacks, precooked foods, other oils and soft drinks). Core-foods DP was inversely associated with BMIz (B = -0.07, p = 0.034), meanwhile the Poor-quality DP was directly associated with triglycerides (B = 0.09, p = 0.015) and higher overweight odds (OR:1.33; 95% CI:1.13–1.56), and inversely with HDLz (B = −0.08, p = 0.036). Conclusion: Poor-quality DP was directly associated with cardiometabolic risk markers in preschool-aged children, emphasizing the importance of diet in preventing the early onset of obesity and cardiometabolic disorders. Impact: This study highlights the impact of dietary patterns on cardiometabolic health in preschool children. A poor-quality dietary pattern is directly associated with BMI and triglycerides and inversely associated with HDL cholesterol, which may contribute to a worse cardiometabolic profile. In contrast, adherence to a core-foods pattern is inversely associated with BMI. These findings reinforce the importance of early nutrition education in preventing obesity and cardiometabolic disorders. This article provides evidence of diet-related metabolic risks in early life to limited existing literature and the need for interventions that promote healthier eating habits from an early age to improve long-term health outcomes.
000171179 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII/FI22-00166
000171179 540__ $$9info:eu-repo/semantics/embargoedAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000171179 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000171179 700__ $$aGispert-Llauradó, Mariona
000171179 700__ $$aEscribano, Joaquin
000171179 700__ $$aJurado-Castro, Jose Manuel
000171179 700__ $$aBabio, Nancy
000171179 700__ $$aLeis, Rosaura
000171179 700__ $$0(orcid)0000-0003-0454-653X$$aMoreno, Luis A.$$uUniversidad de Zaragoza
000171179 700__ $$aNavas-Carretero, Santiago
000171179 700__ $$aCorella, Dolores
000171179 700__ $$aMoreira, Ana
000171179 700__ $$aCastro-Collado, Cristina
000171179 700__ $$aVázquez-Cobela, Rocío
000171179 700__ $$aAlcázar, Mireia
000171179 700__ $$aMiguel-Berges, María L.$$uUniversidad de Zaragoza
000171179 700__ $$aMartinez, J. Alfredo
000171179 700__ $$aPastor-Villaescusa, Belén
000171179 700__ $$aPicáns-Leis, Rosaura
000171179 700__ $$aMimbrero, Gisela
000171179 700__ $$0(orcid)0000-0001-6173-5850$$aDe Miguel-Etayo, Pilar
000171179 700__ $$aFlores-Rojas, Katherine
000171179 700__ $$aGil-Campos, Mercedes
000171179 700__ $$aSalas-Salvadó, Jordi
000171179 700__ $$aLuque, Veronica
000171179 700__ $$aSchröder, Helmut
000171179 700__ $$aFitó, Montse
000171179 700__ $$aPérez-Vega, Karla A.
000171179 700__ $$aSolis Baltodano, Mayela
000171179 700__ $$aMuñoz-Aguayo, Daniel
000171179 700__ $$aBlanchart, Gemma
000171179 700__ $$aGaixas, Sònia
000171179 700__ $$aZomeño, María Dolores
000171179 700__ $$aLorenzo, Isaury
000171179 700__ $$aGil-Campos, Mercedes
000171179 700__ $$aJurado-Castro, José Manuel
000171179 700__ $$aPastor-Villaescusa, Belén
000171179 700__ $$aLlorente-Cantarero, Francisco Jesús
000171179 700__ $$aDe La Torre-Aguilar, María José
000171179 700__ $$aVelasco Aguayo, Inmaculada
000171179 700__ $$aNavas-Carretero, Santiago
000171179 700__ $$aMartínez, J. Alfredo
000171179 700__ $$aMoreno-Aliaga, Maria Jesús
000171179 700__ $$ade Cuevillas García, Begoña
000171179 700__ $$aVázquez-Bolea, Natalia
000171179 700__ $$aGoñi, María
000171179 700__ $$aHernández, María
000171179 700__ $$aPérez Diez, Salomé
000171179 700__ $$aCristobo, Carmen
000171179 700__ $$aBabio, Nancy
000171179 700__ $$aSalas-Salvadó, Jordi
000171179 700__ $$aEscribano, Joaquín
000171179 700__ $$aLuque, Veronica
000171179 700__ $$aFerré, Natalia
000171179 700__ $$aGheorghita, Irina
000171179 700__ $$aFeliu, Albert
000171179 700__ $$aClosa, Ricardo
000171179 700__ $$aAlcázar, Mireia
000171179 700__ $$aMartín, Francisco
000171179 700__ $$aRey, Cristina
000171179 700__ $$aMimbrero, Gisela
000171179 700__ $$aPedraza, Ana
000171179 700__ $$aSalvadó, Olga
000171179 700__ $$aRuiz Velasco, Marta
000171179 700__ $$aBilbao Sustacha, José Ángel
000171179 700__ $$aHerranz Pinilla, Yolanda
000171179 700__ $$aRios, Lidia
000171179 700__ $$aPascual Compte, María
000171179 700__ $$aGarcidueñas-Fimbres, Tany E.
000171179 700__ $$aGómez-Martínez, Carlos
000171179 700__ $$ade las Heras-Delgado, Sara
000171179 700__ $$aSimón, Olga
000171179 700__ $$ade la Torre, Sònia
000171179 700__ $$aTudela, Càrol
000171179 700__ $$aValero Sales, Júlia
000171179 700__ $$aMoroño García, Sara
000171179 700__ $$aLeis, Rosaura
000171179 700__ $$aRomero Agrelo, Anabel
000171179 700__ $$aPicáns-Leis, Rosaura
000171179 700__ $$aGarcía-García, Eva
000171179 700__ $$aMosteiro-Losada, Sofia
000171179 700__ $$aPortoles, Olga
000171179 700__ $$aCodoñer Franch, Pilar
000171179 700__ $$aCorella, Dolores
000171179 700__ $$aMartín Carbonell, Vanessa
000171179 700__ $$aSorlí, José V.
000171179 700__ $$aMoreno, Luis A.
000171179 700__ $$aDe Miguel-Etayo, Pilar
000171179 700__ $$aMiguel-Berges, María Luisa
000171179 700__ $$aSantaliestra-Pasias, Alba Mª
000171179 700__ $$aArgente-Arizon, Pilar
000171179 700__ $$aGimenez-Legarre, Natalia
000171179 700__ $$aFlores-Barrantes, Paloma
000171179 700__ $$aPérez-Gimeno, Gloria
000171179 700__ $$aSeral-Cortés, Miguel
000171179 700__ $$aJimeno-Martínez, Andrea
000171179 700__ $$aManeschy, Ivie
000171179 700__ $$aBenedicto, Isabel
000171179 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000171179 7102_ $$11011$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Medic.Prevent.Salud Públ.
000171179 773__ $$g(2026), [34 pp.]$$pPediatr. res.$$tPediatric research$$x0031-3998
000171179 787__ $$tSupplementary information$$whttps://static-content.springer.com/esm/art%3A10.1038%2Fs41390-026-04889-6/MediaObjects/41390_2026_4889_MOESM1_ESM.pdf
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000171179 951__ $$a2026-05-15-14:54:31
000171179 980__ $$aARTICLE