000171204 001__ 171204
000171204 005__ 20260515163945.0
000171204 0247_ $$2doi$$a10.1016/j.hrtlng.2026.102795
000171204 0248_ $$2sideral$$a149244
000171204 037__ $$aART-2026-149244
000171204 041__ $$aeng
000171204 100__ $$aMartínez Mihara, Mónica Sachi
000171204 245__ $$aManagement of patients with COPD in the emergency department and treatment compliance with clinical guideline recommendations at discharge
000171204 260__ $$c2026
000171204 5060_ $$aAccess copy available to the general public$$fUnrestricted
000171204 5203_ $$aBackground
Chronic obstructive pulmonary disease (COPD) exacerbations are a frequent cause of emergency department visits and are associated with high morbidity, mortality, and healthcare costs. These visits represent an opportunity to optimize patient management and align treatment with guideline recommendations, particularly regarding inhaled triple therapy.
Objectives
To describe the clinical characteristics and management of COPD patients in the emergency department and to identify factors associated with inhaled triple therapy prescription at discharge.
Methods
Retrospective observational study including patients aged >18 years attended at the emergency department of the Hospital Clínico Universitario (Zaragoza, Spain) between July and December 2022, with a diagnosis of COPD exacerbation at discharge. Demographic, clinical, laboratory, and therapeutic variables were analyzed. Logistic regression identified independent predictors of inhaled triple therapy prescription at discharge.
Results
A total of 227 patients were included (mean age: 74.4 years; 70.9% male). Most (93.4%) had a prior COPD diagnosis, and 41.0% were already on maintenance inhaled triple therapy. At discharge, inhaled triple therapy was prescribed in 53.8% of the cases. Independent variables associated with triple therapy prescription included prior use of inhaled triple therapy (odds ratio [OR]:9.4), long-term home oxygen therapy (OR:4.3), and influenza vaccination (OR:3.1). Six months after discharge, 36.0% of patients required hospital admission for COPD exacerbation.
Conclusions
One-third of COPD patients discharged from the emergency department do not receive guideline-recommended inhaled triple therapy. Interventions aimed at standardizing and optimizing emergency department management are needed to improve adherence to clinical guidelines and improve patient outcomes.
000171204 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000171204 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000171204 700__ $$aPérez Pañart, Isabel
000171204 700__ $$aSánchez Salamero, María
000171204 700__ $$aCampos Picontó, Eva
000171204 700__ $$aCanales Villa, Sara Patricia
000171204 700__ $$aLatorre, Víctor
000171204 700__ $$0(orcid)0000-0003-1359-6424$$aSáenz Abad, Daniel$$uUniversidad de Zaragoza
000171204 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000171204 773__ $$g79, 7 (2026), 102795$$pHeart lung$$tHEART & LUNG$$x0147-9563
000171204 8564_ $$s582837$$uhttps://zaguan.unizar.es/record/171204/files/texto_completo.pdf$$yVersión publicada
000171204 8564_ $$s2261984$$uhttps://zaguan.unizar.es/record/171204/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000171204 909CO $$ooai:zaguan.unizar.es:171204$$particulos$$pdriver
000171204 951__ $$a2026-05-15-14:55:00
000171204 980__ $$aARTICLE