32188 20170504094306.0 doi 10.1155/2014/905129 sideral 86583 ART-2014-86583 eng (orcid)0000-0002-9325-9964 Del Buey, M.A. Assessment of corneal biomechanical properties and intraocular pressure in myopic Spanish healthy population 2014 Access copy available to the general public Unrestricted Purpose. To examine biomechanical parameters of the cornea in myopic eyes and their relationship with the degree of myopia in a western healthy population. Methods. Corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann correlated intraocular pressure (IOP), and corneal compensated IOP (IOPcc) were measured using the ocular response analyzer (ORA) in 312 eyes of 177 Spanish subjects aged between 20 and 56 years. Refraction was expressed as spherical equivalent (SE), which ranged from 0 to -16.50 diopters (D) (mean: -3.88 ± 2.90 D). Subjects were divided into four groups according to their refractive status: group 1 or control group: emmetropia (-0.50 = SE < 0.50); group 2: low myopia (-0.75 = SE < 3.00 D); group 3: moderate myopia (-3.00 = SE = -6.00D); and group 3: high myopia (SE greater than -6.00D). We analyzed the relationship between corneal biomechanicsmeasuredwithORAand SE. Results. CHin the emmetropia, lowmyopia,moderatemyopia, and highmyopia groups was 11.13 ± 0.98, 11.49 ± 1.25, 10.52 ± 1.54, and 10.35 ± 1.33mmHg, respectively. CH in the highly myopic group was significantly lower than that in the emmetropic group (¿ = 0.07) and low myopic group (¿ = 0.035); however, there were no differences with the moderate myopic group (¿ = 0.872). There were no statistically significant differences regarding IOP among the four groups (¿ > 0.05); nevertheless, IOPcc was significantly higher in the moderatelymyopic (15.47±2.47mmHg) and highlymyopic (16.14± 2.59mmHg) groups than in the emmetropia (15.15 ± 2.06mmHg) and low myopia groups (14.53 ± 2.37mmHg). No correlation between age and the measured parameters was found. CH and IOPcc were weakly but significantly correlated with SE (¿ = 0.171, ¿ = 0.002 and ¿ = -0.131, ¿ = 0.021, resp.). Conclusions. Present study showed only a very weak, but significant, correlation between CHand refractive error, with CH being lower in both moderately and highlymyopic eyes than that in the emmetropic and low myopic eyes.These changes in biomechanical properties of the cornea may have an impact on IOP measurement, increasing the risk of glaucoma info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 1.425 2014 OPHTHALMOLOGY 37 / 57 = 0.649 2014 Q3 T2 MEDICINE, RESEARCH & EXPERIMENTAL 92 / 123 = 0.748 2014 Q3 T3 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Lavilla, L. (orcid)0000-0001-9876-5850 Ascaso, F.J. Universidad de Zaragoza (orcid)0000-0002-2959-0628 Lanchares, E. Universidad de Zaragoza Huerva, V. Cristóbal, J.A. Universidad de Zaragoza 1004 646 Universidad de Zaragoza Departamento de Cirugía, Ginecología y Obstetricia Oftalmología 5004 605 Universidad de Zaragoza Departamento de Ingeniería Mecánica Mec. de Medios Contínuos y Teor. de Estructuras 2014 (2014), 905129 [6 pp.] J. Ophthalmol. Journal of Ophthalmology 2090-004X 2035596 http://zaguan.unizar.es/record/32188/files/texto_completo.pdf Versión publicada 98864 http://zaguan.unizar.es/record/32188/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:32188 articulos driver 2017-05-04-09:41:37 ARTICLE