000032196 001__ 32196
000032196 005__ 20210121082900.0
000032196 0247_ $$2doi$$a10.1186/s13075-015-0789-9
000032196 0248_ $$2sideral$$a92328
000032196 037__ $$aART-2015-92328
000032196 041__ $$aeng
000032196 100__ $$aSanada, K.
000032196 245__ $$aEffects of non-pharmacological interventions on inflammatory biomarker expression in patients with fibromyalgia: A systematic review
000032196 260__ $$c2015
000032196 5060_ $$aAccess copy available to the general public$$fUnrestricted
000032196 5203_ $$aIntroduction: Fibromyalgia (FM) is a prevalent disorder. However, few studies have evaluated the effect of treatment interventions on biomarker expression. The aim of this review was to explore the efficacy of non-pharmacological interventions on inflammatory biomarker expression, specifically cytokines, neuropeptides and C-reactive protein (CRP), in FM patients. Method: A literature search using PubMed, EMBASE, PsycINFO and the Cochrane library was performed from January 1990 to March 2015. Randomized controlled trials (RCTs) and non-RCTs published in English, French or Spanish were eligible. Results: Twelve articles with a total of 536 participants were included. After exercise, multidisciplinary, or dietary interventions in FM patients, interleukin (IL) expression appeared reduced, specifically serum IL-8 and IL-6 (spontaneous, lipopolysaccharide (LPS)-induced, or serum). Furthermore, the changes to insulin-like growth factor 1 (IGF-1) levels might indicate a beneficial role for fatigue in obese FM patients. In contrast, evidence of changes in neuropeptide and CRP levels seemed inconsistent. Conclusion: Despite minimal evidence, our findings indicate that exercise interventions might act as an anti-inflammatory treatment in FM patients and ameliorate inflammatory status, especially for pro-inflammatory cytokines. Additional RCTs focused on the changes to inflammatory biomarker expression after non-pharmacological interventions in FM patients are needed.
000032196 536__ $$9info:eu-repo/grantAgreement/ES/MINECO/PSI2014-56303-REDT$$9info:eu-repo/grantAgreement/ES/MICINN/ISCIII-RD06-0018-0017
000032196 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000032196 590__ $$a3.979$$b2015
000032196 591__ $$aRHEUMATOLOGY$$b8 / 31 = 0.258$$c2015$$dQ2$$eT1
000032196 592__ $$a1.955$$b2015
000032196 593__ $$aImmunology$$c2015$$dQ1
000032196 593__ $$aRheumatology$$c2015$$dQ1
000032196 593__ $$aImmunology and Allergy$$c2015$$dQ1
000032196 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000032196 700__ $$aAlda Díez, M.
000032196 700__ $$0(orcid)0000-0001-6261-3724$$aSalas Valero, M.
000032196 700__ $$0(orcid)0000-0001-5566-9746$$aPérez-Yus, M.C.$$uUniversidad de Zaragoza
000032196 700__ $$aDemarzo, M.M.P.
000032196 700__ $$aGarcía-Toro, M.
000032196 700__ $$0(orcid)0000-0002-3797-4218$$aGarcía-Campayo, J.$$uUniversidad de Zaragoza
000032196 7102_ $$11007$$2745$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Psiquiatría
000032196 7102_ $$14009$$2680$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Person.Eval.Trat.Psicoló.
000032196 773__ $$g17, 272 (2015), [16 pp.]$$pArthritis res. ther.$$tARTHRITIS RESEARCH & THERAPY$$x1478-6354
000032196 8564_ $$s1044190$$uhttps://zaguan.unizar.es/record/32196/files/texto_completo.pdf$$yVersión publicada
000032196 8564_ $$s105017$$uhttps://zaguan.unizar.es/record/32196/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000032196 909CO $$ooai:zaguan.unizar.es:32196$$particulos$$pdriver
000032196 951__ $$a2021-01-21-08:15:16
000032196 980__ $$aARTICLE