000032214 001__ 32214
000032214 005__ 20210121082901.0
000032214 0247_ $$2doi$$a10.1515/jpm-2015-2003
000032214 0248_ $$2sideral$$a92347
000032214 037__ $$aART-2015-92347
000032214 041__ $$aeng
000032214 100__ $$aAgustín Oliva, A.
000032214 245__ $$aRisk factors for premature aging of placenta: comparative study of perinatal outcomes between grannum grade III placentas and grannum grade I-II placentas
000032214 260__ $$c2015
000032214 5060_ $$aAccess copy available to the general public$$fUnrestricted
000032214 5203_ $$aIntroduction: The placenta aging has been related with intrauterine fetal growth, low maternal age, Caucasian, multiparity, hypertensive states and smoking habit. Grannum P. classification is the most used for its assessment. The association between grade III placenta (G3P) and ex-smoking or smokeexposed pregnants has not been studied
Main outcome: To asses if smoking, being an ex-smoker or a passive-smoker is a risk factor for developing grade III placenta, as well as if there is a smoking-free period of time to avoid the effect of smoking over placenta
Material and methods: A retrospective case-control study of single pregnancies followed-up at the Obstetric Ultrasound Unit between January 2013 and January 2014. Placental grading according to Grannum classification was stablished through abdominal approach between 34-36 weeks of gestation and two groups were established: grade III placenta and grade I-II placenta (G1-2P)
Maternal and paternal characteristics, type of delivery and perinatal outcomes were collected
Results: Baseline characteristics were similar between the two groups. In G3P the incidence of hypertensive disease of pregnancy was higher(p=0,0107). The percentage was similar for premature birth, 1st and 5th minute Apgar, type of delivery and cesarean due to risk of loss of fetal wellbeing. A lower neonatal weight was found in G3P, at the same median days at delivery, with a mean difference of 148,156(p=0,008313. Regarding weight percentile, it was found a p35 in G3P and a p47,5 in G1- 2P(p=0,08235)
15% of the total pregnant were smokers. In G3P group it was found a higher frequency of smokers and ex-smokers since 1st trimester of pregnancy (p=0.0001), as well as pregnant non-smokers with an smoking partner(p=0,0001). There was an strong evidence for association between pregnant smokers and smoking partners(p=0,0001). No difference was found regarding to neonatal weight comparing smokers, ex-smokers and ex-smokers since 1st trimester of pregnancy. The length of pregnancy was lower between G3P pregnant smokers compared to G1-2P pregnant smokers, with a mean difference of 8 days (p=0,00091)
Conclusions: There is a strong evidence for association between smoking during pregnancy, quitting smoking at the beginning of the pregnancy or being a passive smoker with development of G3P
Some pregnant smokers don`t develop premature aging of placenta, it could be due to either other parameters or a later aging (data were collected between 34-36 weeks). The association between quitting smoking at the beginning of the pregnancy and not having a smoking partner reduces the risk of developing G3P
000032214 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000032214 590__ $$a1.798$$b2015
000032214 591__ $$aPEDIATRICS$$b46 / 120 = 0.383$$c2015$$dQ2$$eT2
000032214 591__ $$aOBSTETRICS & GYNECOLOGY$$b42 / 80 = 0.525$$c2015$$dQ3$$eT2
000032214 592__ $$a0.856$$b2015
000032214 593__ $$aPediatrics, Perinatology and Child Health$$c2015$$dQ1
000032214 593__ $$aObstetrics and Gynecology$$c2015$$dQ2
000032214 655_4 $$ainfo:eu-repo/semantics/conferenceObject$$vinfo:eu-repo/semantics/publishedVersion
000032214 700__ $$aDiaz Rabasa, M.B.
000032214 700__ $$aSaviron Cornudella, R.
000032214 700__ $$aLázaro García, V.E.
000032214 700__ $$aMoreno Pérez, R.
000032214 700__ $$aPérez Pérez, P.
000032214 700__ $$aGarrido Fernández, P.
000032214 700__ $$aDe Diego Allué, E.
000032214 700__ $$0(orcid)0000-0002-3007-302X$$aEsteban Escaño, L.
000032214 700__ $$aLerma Puertas, D.
000032214 773__ $$g43, S1 (2015), P-0183$$pJ. perinat. med.$$tJOURNAL OF PERINATAL MEDICINE$$x0300-5577
000032214 8564_ $$s106680$$uhttps://zaguan.unizar.es/record/32214/files/texto_completo.pdf$$yVersión publicada
000032214 8564_ $$s134354$$uhttps://zaguan.unizar.es/record/32214/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000032214 909CO $$ooai:zaguan.unizar.es:32214$$particulos$$pdriver
000032214 951__ $$a2021-01-21-08:15:57
000032214 980__ $$aARTICLE