32488 20170504094304.0 doi 10.1186/1746-6148-10-59 sideral 86668 ART-2014-86668 eng Garrido, V. Simultaneous infections by different Salmonella strains in mesenteric lymph nodes of finishing pigs 2014 Access copy available to the general public Unrestricted Background Salmonellosis is a major worldwide zoonosis, and Salmonella-infected finishing pigs are considered one of the major sources of human infections in developed countries. Baseline studies on salmonellosis prevalence in fattening pigs in Europe are based on direct pathogen isolation from mesenteric lymph nodes (MLN). This procedure is considered the most reliable for diagnosing salmonellosis in apparently healthy pigs. The presence of simultaneous infections by different Salmonella strains in the same animal has never been reported and could have important epidemiological implications. Results Fourteen finishing pigs belonging to 14 farms that showed high salmonellosis prevalence and a variety of circulating Salmonella strains, were found infected by Salmonella spp, and 7 of them were simultaneously infected with strains of 2 or 3 different serotypes. Typhimurium isolates showing resistance to several antimicrobials and carrying mobile integrons were the most frequently identified in the colonized MLN. Four animals were found infected by Salmonella spp. of a single serotype (Rissen or Derby) but showing 2 or 3 different antimicrobial resistance profiles, without evidence of mobile genetic element exchange in vivo. Conclusion This is the first report clearly demonstrating that pigs naturally infected by Salmonella may harbour different Salmonella strains simultaneously. This may have implications in the interpretation of results from baseline studies, and also help to better understand human salmonellosis outbreaks and the horizontal transmission of antimicrobial resistance genes. info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 1.777 2014 VETERINARY SCIENCES 21 / 132 = 0.159 2014 Q1 T1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Sánchez, S. San Román, B. Zabalza-Baranguá, A. Díaz-Tendero, Y. de Frutos, C. (orcid)0000-0001-5442-7702 Mainar-Jaime, R. Universidad de Zaragoza Grilló, M.J 1009 773 Universidad de Zaragoza Departamento de Patología Animal Sanidad Animal 10, 59 (2014), [6 pp.] BMC Vet. Res. BMC VETERINARY RESEARCH 1746-6148 198468 http://zaguan.unizar.es/record/32488/files/texto_completo.pdf Versión publicada 110818 http://zaguan.unizar.es/record/32488/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:32488 articulos driver 2017-05-04-09:41:21 ARTICLE